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LIM and senescent cell antigen-like-containing domain protein

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Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.

Below are the list of possible LIM and senescent cell antigen-like-containing domain protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

LIM and senescent cell antigen-like-containing domain protein 1

 LIM and senescent cell antigen-like-containing domain protein 1 ELISA Kit
 LIM and senescent cell antigen-like-containing domain protein 1 Recombinant
 LIM and senescent cell antigen-like-containing domain protein 1 Antibody
Also known as LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1).
LIMS1: Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINC
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H. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Cellular Component: focal adhesion; intercellular junction; perinuclear region of cytoplasm; protein complex

Molecular Function: protein binding; protein kinase binding; zinc ion binding

Biological Process: cell-cell adhesion; cell-matrix adhesion; chordate embryonic development; establishment and/or maintenance of cell polarity; establishment of protein localization; intercellular junction assembly and maintenance; negative regulation of apoptosis; negative regulation of epithelial cell proliferation; negative regulation of transcription, DNA-dependent; positive regulation of focal adhesion formation; positive regulation of GTPase activity; protein heterooligomerization
 Lims1 ELISA Kit
 Lims1 Recombinant
 Lims1 Antibody
 Pinch1 ELISA Kit
 Pinch1 Recombinant
 Pinch1 Antibody
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LIM and senescent cell antigen-like-containing domain protein 2

 LIM and senescent cell antigen-like-containing domain protein 2 ELISA Kit
 LIM and senescent cell antigen-like-containing domain protein 2 Recombinant
 LIM and senescent cell antigen-like-containing domain protein 2 Antibody
Also known as LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2).
LIMS2: Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2q14.3

Cel
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lular Component: cytosol; focal adhesion

Disease: Muscular Dystrophy, Limb-girdle, Type 2w
 LIMS2 ELISA Kit
 LIMS2 Recombinant
 LIMS2 Antibody
 PINCH2 ELISA Kit
 PINCH2 Recombinant
 PINCH2 Antibody
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LIM and senescent cell antigen-like-containing domain protein 3

 LIM and senescent cell antigen-like-containing domain protein 3 ELISA Kit
 LIM and senescent cell antigen-like-containing domain protein 3 Recombinant
 LIM and senescent cell antigen-like-containing domain protein 3 Antibody
Also known as LIM and senescent cell antigen-like-containing domain protein 3 (Particularly interesting new Cys-His protein 3) (PINCH-3).
LIMS3: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2q13
 LIMS3 ELISA Kit
 LIMS3 Recombinant
 LIMS3 Antibody
 PINCH3 ELISA Kit
 PINCH3 Recombinant
 PINCH3 Antibody
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LIM and senescent cell antigen-like-containing domain protein 4

 LIM and senescent cell antigen-like-containing domain protein 4 ELISA Kit
 LIM and senescent cell antigen-like-containing domain protein 4 Recombinant
 LIM and senescent cell antigen-like-containing domain protein 4 Antibody
Also known as LIM and senescent cell antigen-like-containing domain protein 4 (LIM and senescent cell antigen-like-containing domain protein 3-like).
LIMS3L:

Chromosomal Location of Human Ortholog: 2q13

Molecular Function: protein binding
 LIMS4 ELISA Kit
 LIMS4 Recombinant
 LIMS4 Antibody
 LIMS3L ELISA Kit
 LIMS3L Recombinant
 LIMS3L Antibody
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