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LINE-1 retrotransposable element ORF2 protein

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Has a reverse transcriptase activity required for target-primed reverse transcription of the LINE-1 element mRNA, a crucial step in LINE-1 retrotransposition. Has also an endonuclease activity that allows the introduction of nicks in the chromosomal target DNA. Cleaves DNA in AT-rich regions between a 5' stretch of purines and a 3' stretch of pyrimidines, corresponding to sites of LINE-1 integration in the genome.

Below are the list of possible LINE-1 retrotransposable element ORF2 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

LINE-1 retrotransposable element ORF2 protein

 LINE-1 retrotransposable element ORF2 protein ELISA Kit
 LINE-1 retrotransposable element ORF2 protein Recombinant
 LINE-1 retrotransposable element ORF2 protein Antibody
Also known as LINE-1 retrotransposable element ORF2 protein (ORF2p).
LORF2: Has a reverse transcriptase activity required for target-primed reverse transcription of the LINE-1 element mRNA, a cruci
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al step in LINE-1 retrotransposition. Has also an endonuclease activity that allows the introduction of nicks in the chromosomal target DNA. Cleaves DNA in AT-rich regions between a 5' stretch of purines and a 3' stretch of pyrimidines, corresponding to sites of LINE-1 integration in the genome

Protein type: EC 2.7.7.49
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