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Linker for activation of T-cells family

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Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Below are the list of possible Linker for activation of T-cells family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Linker for activation of T-cells family member 1

 Linker for activation of T-cells family member 1 ELISA Kit
 Linker for activation of T-cells family member 1 Recombinant
 Linker for activation of T-cells family member 1 Antibody
Also known as Linker for activation of T-cells family member 1 (36 kDa phospho-tyrosine adapter protein) (pp36) (p36-38).
LAT: an adaptor protein involved in T-cell antigen receptor (TCR) signal transduction pathway. Plays an important role downstream of protein tyrosine kinases. Essential for TCR-mediated Ras-Erk activation and calcium flux.

Protein type: Adaptor/scaffold; Membrane prot
>>>
ein, integral

Cellular Component: immunological synapse; integral to membrane; integral to plasma membrane; intercellular junction; signalosome

Molecular Function: protein binding; protein kinase binding; receptor signaling protein activity; SH3/SH2 adaptor activity

Biological Process: calcium-mediated signaling; cellular defense response; gene expression; homeostasis of number of cells; immune response; inflammatory response; integrin-mediated signaling pathway; lymphocyte homeostasis; Ras protein signal transduction; regulation of T cell activation; transmembrane receptor protein tyrosine kinase signaling pathway
 Lat ELISA Kit
 Lat Recombinant
 Lat Antibody
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Linker for activation of T-cells family member 2

 Linker for activation of T-cells family member 2 ELISA Kit
 Linker for activation of T-cells family member 2 Recombinant
 Linker for activation of T-cells family member 2 Antibody
Also known as Linker for activation of T-cells family member 2 (Linker for activation of B-cells) (Membrane-associated adapter molecule) (Non-T-cell activation linker) (Williams-Beuren syndrome chromosomal region 15 protein homolog).
LAB: linker for activation of B cells (LAB) is an adaptor protein. B cell antigen receptor signaling leads to its phosphorylation and interaction with the adaptor protein Grb2. Decreased expression leads to a reduction in BCR-mediated calcium flux and Erk activation. Localized to lipid rafts.

Protein type: Adaptor/scaffold; Membrane protein, integral >>>
r>
Cellular Component: lipid raft

Molecular Function: SH2 domain binding

Biological Process: B cell activation; B cell receptor signaling pathway; calcium-mediated signaling
 Lat2 ELISA Kit
 Lat2 Recombinant
 Lat2 Antibody
 Lab ELISA Kit
 Lab Recombinant
 Lab Antibody
 Ntal ELISA Kit
 Ntal Recombinant
 Ntal Antibody
 Wbscr15 ELISA Kit
 Wbscr15 Recombinant
 Wbscr15 Antibody
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