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Lysine-specific histone demethylase

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Below are the list of possible Lysine-specific histone demethylase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Lysine-specific histone demethylase 1

 Lysine-specific histone demethylase 1 ELISA Kit
 Lysine-specific histone demethylase 1 Recombinant
 Lysine-specific histone demethylase 1 Antibody
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role.
 lsd1 ELISA Kit
 lsd1 Recombinant
 lsd1 Antibody
 saf110 ELISA Kit
 saf110 Recombinant
 saf110 Antibody
 swm1 ELISA Kit
 swm1 Recombinant
 swm1 Antibody
 SPBC146.09c ELISA Kit
 SPBC146.09c Recombinant
 SPBC146.09c Antibody
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Lysine-specific histone demethylase 1 homolog 1

 Lysine-specific histone demethylase 1 homolog 1 ELISA Kit
 Lysine-specific histone demethylase 1 homolog 1 Recombinant
 Lysine-specific histone demethylase 1 homolog 1 Antibody
Also known as Lysine-specific histone demethylase 1 homolog 1 (Flavin-containing amine oxidase domain-containing protein 1) (Protein LSD1-LIKE 1).
Probable histone demethylase.
 Os02g0755200 ELISA Kit
 Os02g0755200 Recombinant
 Os02g0755200 Antibody
 LOC_Os02g51880 ELISA Kit
 LOC_Os02g51880 Recombinant
 LOC_Os02g51880 Antibody
 P0627E03.23 ELISA Kit
 P0627E03.23 Recombinant
 P0627E03.23 Antibody
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Lysine-specific histone demethylase 1 homolog 2

 Lysine-specific histone demethylase 1 homolog 2 ELISA Kit
 Lysine-specific histone demethylase 1 homolog 2 Recombinant
 Lysine-specific histone demethylase 1 homolog 2 Antibody
Also known as Lysine-specific histone demethylase 1 homolog 2 (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2).
Probable histone demethylase.
 Os08g0143400 ELISA Kit
 Os08g0143400 Recombinant
 Os08g0143400 Antibody
 LOC_Os08g04780 ELISA Kit
 LOC_Os08g04780 Recombinant
 LOC_Os08g04780 Antibody
 P0025F03.17-1 ELISA Kit
 P0025F03.17-1 Recombinant
 P0025F03.17-1 Antibody
 P0025F03.17-2 ELISA Kit
 P0025F03.17-2 Recombinant
 P0025F03.17-2 Antibody
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Lysine-specific histone demethylase 1 homolog 3

 Lysine-specific histone demethylase 1 homolog 3 ELISA Kit
 Lysine-specific histone demethylase 1 homolog 3 Recombinant
 Lysine-specific histone demethylase 1 homolog 3 Antibody
Also known as Lysine-specific histone demethylase 1 homolog 3 (Flavin-containing amine oxidase domain-containing protein 3) (Protein FLOWERING LOCUS D-LIKE) (Protein LSD1-LIKE 3).
Probable histone demethylase.
 Os04g0560300 ELISA Kit
 Os04g0560300 Recombinant
 Os04g0560300 Antibody
 LOC_Os04g47270 ELISA Kit
 LOC_Os04g47270 Recombinant
 LOC_Os04g47270 Antibody
 OSJNBa0084K11.6 ELISA Kit
 OSJNBa0084K11.6 Recombinant
 OSJNBa0084K11.6 Antibody
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Lysine-specific histone demethylase 1A

 Lysine-specific histone demethylase 1A ELISA Kit
 Lysine-specific histone demethylase 1A Recombinant
 Lysine-specific histone demethylase 1A Antibody
Also known as Lysine-specific histone demethylase 1A (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2).
LSD1: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di
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-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity. Also acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and mediating demethylation of H3K9me, a specific tag for epigenetic transcriptional repression. The presence of PRKCB in ANDR-containing complexes, which mediates phosphorylation of 'Thr- 6' of histone H3 (H3T6ph), a specific tag that prevents demethylation H3K4me, prevents H3K4me demethylase activity of KDM1A. Demethylates di-methylated 'Lys-370' of p53/TP53 which prevents interaction of p53/TP53 with TP53BP1 and represses p53/TP53-mediated transcriptional activation. Demethylates and stabilizes the DNA methylase DNMT1. Required for gastrulation during embryogenesis. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Component of a RCOR/GFI/KDM1A/HDAC complex. Interacts directly with GFI1 and GFI1B. Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B, KDM1A, RCOR1 and PHF21A. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. In the complex, RCOR1/CoREST strongly enhances the demethylase activity and protects it from the proteasome while PHF21A/BHC80 inhibits the demethylase activity. Interacts with the androgen receptor (AR). Interacts with ASXL1. Ubiquitously expressed. Belongs to the flavin monoamine oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Demethylase; EC 1.-.-.-; Nuclear receptor co-regulator; Oxidoreductase; Transcription factor

Chromosomal Location of Human Ortholog: 1p36.12

Cellular Component: nuclear chromatin; nuclear chromosome, telomeric region; nucleoplasm; nucleus; protein complex; transcription factor complex

Molecular Function: androgen receptor binding; chromatin binding; demethylase activity; enzyme binding; FAD binding; histone deacetylase activity; histone demethylase activity; histone demethylase activity (H3-K4 specific); histone demethylase activity (H3-K9 specific); ligand-dependent nuclear receptor transcription coactivator activity; MRF binding; oxidoreductase activity; p53 binding; protein binding; telomeric DNA binding; transcription factor binding

Biological Process: blood coagulation; histone H3-K9 demethylation; muscle cell development; negative regulation of DNA binding; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of protein binding; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of histone ubiquitination; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein amino acid demethylation; regulation of transcription from RNA polymerase II promoter

Disease: Cleft Palate, Psychomotor Retardation, And Distinctive Facial Features
 KDM1A ELISA Kit
 KDM1A Recombinant
 KDM1A Antibody
 AOF2 ELISA Kit
 AOF2 Recombinant
 AOF2 Antibody
 KDM1 ELISA Kit
 KDM1 Recombinant
 KDM1 Antibody
 KIAA0601 ELISA Kit
 KIAA0601 Recombinant
 KIAA0601 Antibody
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Lysine-specific histone demethylase 1B

 Lysine-specific histone demethylase 1B ELISA Kit
 Lysine-specific histone demethylase 1B Recombinant
 Lysine-specific histone demethylase 1B Antibody
Also known as Lysine-specific histone demethylase 1B (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2).
AOF1: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri- me
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thylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys- 36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. Belongs to the flavin monoamine oxidase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Oxidoreductase

Cellular Component: nucleus

Molecular Function: FAD binding; zinc ion binding

Biological Process: DNA methylation during gametogenesis; genetic imprinting
 Kdm1b ELISA Kit
 Kdm1b Recombinant
 Kdm1b Antibody
 Aof1 ELISA Kit
 Aof1 Recombinant
 Aof1 Antibody
 Lsd2 ELISA Kit
 Lsd2 Recombinant
 Lsd2 Antibody
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Lysine-specific histone demethylase 2

 Lysine-specific histone demethylase 2 ELISA Kit
 Lysine-specific histone demethylase 2 Recombinant
 Lysine-specific histone demethylase 2 Antibody
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role.
 lsd2 ELISA Kit
 lsd2 Recombinant
 lsd2 Antibody
 saf140 ELISA Kit
 saf140 Recombinant
 saf140 Antibody
 swm2 ELISA Kit
 swm2 Recombinant
 swm2 Antibody
 SPAC23E2.02 ELISA Kit
 SPAC23E2.02 Recombinant
 SPAC23E2.02 Antibody
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Proteins Root Name Listing
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