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Lysyl oxidase

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Active on elastin and collagen substrates.

Below are the list of possible Lysyl oxidase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Lysyl oxidase homolog 1

 Lysyl oxidase homolog 1 ELISA Kit
 Lysyl oxidase homolog 1 Recombinant
 Lysyl oxidase homolog 1 Antibody
Also known as Lysyl oxidase homolog 1 (Lysyl oxidase 2) (Lysyl oxidase-like protein 1).
LOXL1: Active on elastin and collagen substrates. Genetic variations in LOXL1 are a cause of susceptibility to exfoliation syndrome (XFS); also called exfoliation glaucoma (XFG). XFS is a disorder characterized by accumulation of abnormal fibrillar deposits in the anterior segment of the eye. In addition to being a cause of glaucoma and glaucomatous optic neuropathy, exfoliation syndrome has also been associated with lens zonule weakness, cataract formation, and systemic vascular complications due to dep
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osition of exfoliation material in extraocular tissues. Susceptibility to exfoliation syndrome is conferred by a risk haplotype that includes two LOXL1 coding non-synonymous SNPs (Arg141Leu and Gly153Asp) and one intronic SNP. Arg141Leu and Gly153Asp are sufficient to confer disease susceptibility in some populations. Belongs to the lysyl oxidase family.

Protein type: EC 1.4.3.-; Extracellular matrix; Oxidoreductase; Secreted; Secreted, signal peptide

Cellular Component: acrosome; basement membrane; cytoplasm; extracellular matrix; proteinaceous extracellular matrix

Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; protein binding
 Loxl1 ELISA Kit
 Loxl1 Recombinant
 Loxl1 Antibody
 Lox2 ELISA Kit
 Lox2 Recombinant
 Lox2 Antibody
 Loxl ELISA Kit
 Loxl Recombinant
 Loxl Antibody
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Lysyl oxidase homolog 2

 Lysyl oxidase homolog 2 ELISA Kit
 Lysyl oxidase homolog 2 Recombinant
 Lysyl oxidase homolog 2 Antibody
Also known as Lysyl oxidase homolog 2 (Lysyl oxidase-like protein 2).
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fi
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brous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and probably specifically mediates deamination of histone H3. Involved in epithelial to mesenchymal transition (EMT) and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
 LOXL2 ELISA Kit
 LOXL2 Recombinant
 LOXL2 Antibody
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Lysyl oxidase homolog 2A

 Lysyl oxidase homolog 2A ELISA Kit
 Lysyl oxidase homolog 2A Recombinant
 Lysyl oxidase homolog 2A Antibody
Also known as Lysyl oxidase homolog 2A (Lysyl oxidase-like protein 2A).
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When nuclear, acts as a transcription corepressor and probably specifically mediates deamination of histone H3. Involved in epithelial to mesenchymal transition (EMT) and part
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icipates in repression of E-cadherin, probably by mediating deamination of histone H3. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation (). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding.
 loxl2a ELISA Kit
 loxl2a Recombinant
 loxl2a Antibody
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Lysyl oxidase homolog 2B

 Lysyl oxidase homolog 2B ELISA Kit
 Lysyl oxidase homolog 2B Recombinant
 Lysyl oxidase homolog 2B Antibody
Also known as Lysyl oxidase homolog 2B (Lysyl oxidase-like protein 2B).
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and probably specifically mediates
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deamination of histone H3. Involved in epithelial to mesenchymal transition (EMT) and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
 loxl2b ELISA Kit
 loxl2b Recombinant
 loxl2b Antibody
 si:dkeyp-32b1.1 ELISA Kit
 si:dkeyp-32b1.1 Recombinant
 si:dkeyp-32b1.1 Antibody
 zgc:158414 ELISA Kit
 zgc:158414 Recombinant
 zgc:158414 Antibody
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Lysyl oxidase homolog 3

 Lysyl oxidase homolog 3 ELISA Kit
 Lysyl oxidase homolog 3 Recombinant
 Lysyl oxidase homolog 3 Antibody
Also known as Lysyl oxidase homolog 3 (Lysyl oxidase-like protein 3).
LOXL3: a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at th
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e C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Protein type: EC 1.4.3.-; Oxidoreductase; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p13

Cellular Component: extracellular region; nucleus

Molecular Function: protein binding

Biological Process: epithelial to mesenchymal transition; negative regulation of transcription, DNA-dependent
 LOXL3 ELISA Kit
 LOXL3 Recombinant
 LOXL3 Antibody
 LOXL ELISA Kit
 LOXL Recombinant
 LOXL Antibody
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Lysyl oxidase homolog 4

 Lysyl oxidase homolog 4 ELISA Kit
 Lysyl oxidase homolog 4 Recombinant
 Lysyl oxidase homolog 4 Antibody
Also known as Lysyl oxidase homolog 4 (Lysyl oxidase-like protein 4).
May modulate the formation of a collagenous extracellular matrix.
 LOXL4 ELISA Kit
 LOXL4 Recombinant
 LOXL4 Antibody
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