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MAGE-like protein

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Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35. Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly .

Below are the list of possible MAGE-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

MAGE-like protein 2

 MAGE-like protein 2 ELISA Kit
 MAGE-like protein 2 Recombinant
 MAGE-like protein 2 Antibody
Also known as MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15).
MAGE-L2: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Interacts with TRIM27

Chromosomal Location of Human Ortholog: 15q11.2

Cellu
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lar Component: endosome; nucleus; retromer complex

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of transcription, DNA-dependent; regulation of circadian rhythm; retrograde transport, endosome to Golgi

Disease: Prader-willi Syndrome; Prader-willi-like Syndrome
 MAGEL2 ELISA Kit
 MAGEL2 Recombinant
 MAGEL2 Antibody
 NDNL1 ELISA Kit
 NDNL1 Recombinant
 NDNL1 Antibody
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