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Melanoma antigen

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Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.

Below are the list of possible Melanoma antigen products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Melanoma antigen preferentially expressed in tumors

 Melanoma antigen preferentially expressed in tumors ELISA Kit
 Melanoma antigen preferentially expressed in tumors Recombinant
 Melanoma antigen preferentially expressed in tumors Antibody
Also known as Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma).
PRAME: Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. Belongs to the PRAME family.

Protein type: Cancer Testis Antigen (CTA); Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 22q11.22
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r>Molecular Function: protein binding; retinoic acid receptor binding

Biological Process: negative regulation of apoptosis; negative regulation of cell differentiation; negative regulation of retinoic acid receptor signaling pathway; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation
 PRAME ELISA Kit
 PRAME Recombinant
 PRAME Antibody
 MAPE ELISA Kit
 MAPE Recombinant
 MAPE Antibody
 OIP4 ELISA Kit
 OIP4 Recombinant
 OIP4 Antibody
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