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Mesoderm posterior protein

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Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

Below are the list of possible Mesoderm posterior protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Mesoderm posterior protein 1

 Mesoderm posterior protein 1 ELISA Kit
 Mesoderm posterior protein 1 Recombinant
 Mesoderm posterior protein 1 Antibody
MESP1: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

Protein type: Cell development/differentiation; Transcription factor

Cellular Component: nucleus

Molecular Function: transcription factor activity
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r>Biological Process: cardiac muscle cell differentiation; endothelial cell differentiation; gastrulation; heart looping; heart morphogenesis; lateral mesoderm development; mesodermal cell migration; negative regulation of endodermal cell fate specification; negative regulation of mesodermal cell fate specification; negative regulation of transcription, DNA-dependent; neurogenesis; positive regulation of Notch signaling pathway; positive regulation of striated muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
 Mesp1 ELISA Kit
 Mesp1 Recombinant
 Mesp1 Antibody
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Mesoderm posterior protein 2

 Mesoderm posterior protein 2 ELISA Kit
 Mesoderm posterior protein 2 Recombinant
 Mesoderm posterior protein 2 Antibody
MESP2: Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border
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formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defects in MESP2 are the cause of spondylocostal dysostosis type 2 (SCDO2). An autosomal recessive condition of variable severity associated with vertebral and rib segmentation defects. The main skeletal malformations include fusion of vertebrae, hemivertebrae, fusion of certain ribs, and other rib malformations. Deformity of the chest and spine (severe scoliosis, kyphoscoliosis and lordosis) is a natural consequence of the malformation and leads to a dwarf-like appearance. As the thorax is small, infants frequently have respiratory insufficiency and repeated respiratory infections resulting in life-threatening complications in the first year of life.

Protein type: Cell development/differentiation; Transcription factor

Cellular Component: nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: mesodermal cell migration; Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; somite rostral/caudal axis specification; somitogenesis
 Mesp2 ELISA Kit
 Mesp2 Recombinant
 Mesp2 Antibody
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