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Metabotropic glutamate receptor

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G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.

Below are the list of possible Metabotropic glutamate receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Metabotropic glutamate receptor

 Metabotropic glutamate receptor ELISA Kit
 Metabotropic glutamate receptor Recombinant
 Metabotropic glutamate receptor Antibody
Also known as Metabotropic glutamate receptor (DmGluRA).
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.
 mGluR ELISA Kit
 mGluR Recombinant
 mGluR Antibody
 Glu-RA ELISA Kit
 Glu-RA Recombinant
 Glu-RA Antibody
 GluRA ELISA Kit
 GluRA Recombinant
 GluRA Antibody
 mGluRA ELISA Kit
 mGluRA Recombinant
 mGluRA Antibody
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Metabotropic glutamate receptor 1

 Metabotropic glutamate receptor 1 ELISA Kit
 Metabotropic glutamate receptor 1 Recombinant
 Metabotropic glutamate receptor 1 Antibody
Also known as Metabotropic glutamate receptor 1 (mGluR1).
mGluR1: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol- calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. Homodimer; disulfide-linked. The PPXXF motif binds HOMER1, HOMER2 and HOMER3. Interacts with SIAH1, RYR1, RYR2, ITPR1, SHANK1, SHANK3 and GRASP. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human
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protein are produced by alternative splicing.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q24

Cellular Component: integral to plasma membrane; plasma membrane; postsynaptic density

Molecular Function: G-protein coupled receptor activity; glutamate receptor activity; protein binding

Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; metabotropic glutamate receptor signaling pathway; protein kinase C activation; regulation of synaptic transmission, glutamatergic; synaptic transmission

Disease: Spinocerebellar Ataxia, Autosomal Recessive 13
 GRM1 ELISA Kit
 GRM1 Recombinant
 GRM1 Antibody
 GPRC1A ELISA Kit
 GPRC1A Recombinant
 GPRC1A Antibody
 MGLUR1 ELISA Kit
 MGLUR1 Recombinant
 MGLUR1 Antibody
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Metabotropic glutamate receptor 2

 Metabotropic glutamate receptor 2 ELISA Kit
 Metabotropic glutamate receptor 2 Recombinant
 Metabotropic glutamate receptor 2 Antibody
Also known as Metabotropic glutamate receptor 2 (mGluR2).
mGluR2: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. Belongs to the G-protein coupled receptor 3 family.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: axon; integral to plasma membrane; intracellular; neuron projection; presynaptic membrane

Molecular Fun
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ction: calcium channel regulator activity; group II metabotropic glutamate receptor activity; protein binding

Biological Process: glutamate secretion; regulation of synaptic transmission, glutamatergic; synaptic transmission
 Grm2 ELISA Kit
 Grm2 Recombinant
 Grm2 Antibody
 Gprc1b ELISA Kit
 Gprc1b Recombinant
 Gprc1b Antibody
 Mglur2 ELISA Kit
 Mglur2 Recombinant
 Mglur2 Antibody
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Metabotropic glutamate receptor 3

 Metabotropic glutamate receptor 3 ELISA Kit
 Metabotropic glutamate receptor 3 Recombinant
 Metabotropic glutamate receptor 3 Antibody
Also known as Metabotropic glutamate receptor 3 (mGluR3).
mGluR3: metabotropic glutamate receptor 3, a G-protein coupled receptor for glutamate. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 7q21.1-q21.2

Cellular Component: inte
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gral to plasma membrane; plasma membrane; presynaptic membrane

Molecular Function: G-protein coupled receptor activity; glutamate receptor activity

Biological Process: metabotropic glutamate receptor, adenylate cyclase inhibiting pathway; negative regulation of adenylate cyclase activity; regulation of synaptic transmission, glutamatergic; synaptic transmission
 GRM3 ELISA Kit
 GRM3 Recombinant
 GRM3 Antibody
 GPRC1C ELISA Kit
 GPRC1C Recombinant
 GPRC1C Antibody
 MGLUR3 ELISA Kit
 MGLUR3 Recombinant
 MGLUR3 Antibody
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Metabotropic glutamate receptor 4

 Metabotropic glutamate receptor 4 ELISA Kit
 Metabotropic glutamate receptor 4 Recombinant
 Metabotropic glutamate receptor 4 Antibody
Also known as Metabotropic glutamate receptor 4 (mGluR4).
mGluR4: metabotropic glutamate receptor 3, a G-protein coupled receptor for glutamate. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.

Protein type: Cell development/differentiation; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cytoplasmic vesicle; dendritic
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shaft; integral to plasma membrane; intracellular; neuron projection; presynaptic active zone membrane; terminal button

Molecular Function: calcium-dependent protein binding; calmodulin binding; G-protein coupled receptor activity; glutamate receptor activity; group III metabotropic glutamate receptor activity

Biological Process: activation of MAPK activity; gamma-aminobutyric acid secretion; learning; metabotropic glutamate receptor, adenylate cyclase inhibiting pathway; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of synaptic transmission; neurite development; positive regulation of MAPKKK cascade; regulation of synaptic transmission, glutamatergic; synaptic transmission; synaptic transmission, GABAergic; synaptic transmission, glutamatergic
 Grm4 ELISA Kit
 Grm4 Recombinant
 Grm4 Antibody
 Gprc1d ELISA Kit
 Gprc1d Recombinant
 Gprc1d Antibody
 Mglur4 ELISA Kit
 Mglur4 Recombinant
 Mglur4 Antibody
Table BarTOPTable Bar
 

Metabotropic glutamate receptor 5

 Metabotropic glutamate receptor 5 ELISA Kit
 Metabotropic glutamate receptor 5 Recombinant
 Metabotropic glutamate receptor 5 Antibody
Also known as Metabotropic glutamate receptor 5 (mGluR5).
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
 Grm5 ELISA Kit
 Grm5 Recombinant
 Grm5 Antibody
 Gprc1e ELISA Kit
 Gprc1e Recombinant
 Gprc1e Antibody
 Mglur5 ELISA Kit
 Mglur5 Recombinant
 Mglur5 Antibody
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Metabotropic glutamate receptor 6

 Metabotropic glutamate receptor 6 ELISA Kit
 Metabotropic glutamate receptor 6 Recombinant
 Metabotropic glutamate receptor 6 Antibody
Also known as Metabotropic glutamate receptor 6 (mGluR6).
mGluR6: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Defects in GRM6 are the cause of congenital stationary night blindness type 1B (CSNB1B). This disorder consits of a previously unrecognized, autosomal recessive form of congenital night blindness associated with a negative electroretinogram waveform. Patients are night blind from an early age, and when maximally dark-adapted, they could perceive lights only with an intensity equal to or slightly dimmer th
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an that normally detected by the cone system. ERGs in response to single brief flashes of light have clearly detectable a-waves, which are derived from photoreceptors, and greatly reduced b-waves, which are derived from the second-order inner retinal neurons. ERGs in response to sawtooth flickering light indicate a markedly reduced ON response and a nearly normal OFF response. There is no subjective delay in the perception of suddenly appearing white vs black objects on a gray background. Belongs to the G-protein coupled receptor 3 family.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: endoplasmic reticulum membrane; Golgi membrane; integral to membrane; integral to plasma membrane; presynaptic membrane

Molecular Function: adenylate cyclase inhibiting metabotropic glutamate receptor activity; glutamate receptor activity; group III metabotropic glutamate receptor activity; protein homodimerization activity

Biological Process: detection of light stimulus involved in visual perception; locomotory behavior; metabotropic glutamate receptor signaling pathway; metabotropic glutamate receptor, adenylate cyclase inhibiting pathway; regulation of synaptic transmission, glutamatergic; retina development in camera-type eye; sensory perception of light stimulus; signal transduction; synaptic transmission
 Grm6 ELISA Kit
 Grm6 Recombinant
 Grm6 Antibody
 Gprc1f ELISA Kit
 Gprc1f Recombinant
 Gprc1f Antibody
 Mglur6 ELISA Kit
 Mglur6 Recombinant
 Mglur6 Antibody
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Metabotropic glutamate receptor 7

 Metabotropic glutamate receptor 7 ELISA Kit
 Metabotropic glutamate receptor 7 Recombinant
 Metabotropic glutamate receptor 7 Antibody
Also known as Metabotropic glutamate receptor 7 (mGluR7).
mGluR7: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: asymmetric synapse; axon; cell cortex; cell soma; cell surface; dendrite; dendritic shaft; Golgi apparatus; integral to membrane; integral to plasma
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membrane; membrane; nerve terminal; postsynaptic membrane; presynaptic active zone; presynaptic active zone membrane; presynaptic membrane; protein complex; receptor complex; rough endoplasmic reticulum; synapse; terminal button

Molecular Function: adenylate cyclase inhibiting metabotropic glutamate receptor activity; calcium channel regulator activity; calcium-dependent protein binding; calmodulin binding; glutamate binding; glutamate receptor activity; group III metabotropic glutamate receptor activity; PDZ domain binding; protein homodimerization activity; voltage-gated calcium channel activity

Biological Process: adult behavior; associative learning; behavioral fear response; conditioned taste aversion; memory; metabotropic glutamate receptor, adenylate cyclase inhibiting pathway; multicellular organismal response to stress; negative regulation of cAMP biosynthetic process; negative regulation of glutamate secretion; neurological system process; regulation of synaptic transmission, glutamatergic; sensory perception of sound; short-term memory; synaptic transmission; transmission of nerve impulse
 Grm7 ELISA Kit
 Grm7 Recombinant
 Grm7 Antibody
 Gprc1g ELISA Kit
 Gprc1g Recombinant
 Gprc1g Antibody
 Mglur7 ELISA Kit
 Mglur7 Recombinant
 Mglur7 Antibody
Table BarTOPTable Bar
 

Metabotropic glutamate receptor 8

 Metabotropic glutamate receptor 8 ELISA Kit
 Metabotropic glutamate receptor 8 Recombinant
 Metabotropic glutamate receptor 8 Antibody
Also known as Metabotropic glutamate receptor 8 (mGluR8).
mGluR8: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cell soma; integral to plasma membrane; neuron projection; presynaptic membrane

Molecular Function: G-protein coupled receptor activity; gluta
>>>
mate receptor activity; group III metabotropic glutamate receptor activity

Biological Process: detection of mechanical stimulus involved in sensory perception of pain; metabotropic glutamate receptor, adenylate cyclase inhibiting pathway; negative regulation of cAMP biosynthetic process; regulation of neurotransmitter secretion; regulation of synaptic transmission, glutamatergic; synaptic transmission; synaptic transmission, glutamatergic
 Grm8 ELISA Kit
 Grm8 Recombinant
 Grm8 Antibody
 Gprc1h ELISA Kit
 Gprc1h Recombinant
 Gprc1h Antibody
 Mglur8 ELISA Kit
 Mglur8 Recombinant
 Mglur8 Antibody
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