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Metalloendopeptidase

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Probably involved in maturation of some viral proteins by processing them preferentially at Ala-Gly-|-Ser/Thr/Lys motifs. Does not seem to be responsible for the cleavage of major core proteins.

Below are the list of possible Metalloendopeptidase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Metalloendopeptidase G1

 Metalloendopeptidase G1 ELISA Kit
 Metalloendopeptidase G1 Recombinant
 Metalloendopeptidase G1 Antibody
Probably involved in maturation of some viral proteins by processing them preferentially at Ala-Gly-|-Ser/Thr/Lys motifs. Does not seem to be responsible for the cleavage of major core proteins.
 VACWR078 ELISA Kit
 VACWR078 Recombinant
 VACWR078 Antibody
 G1L ELISA Kit
 G1L Recombinant
 G1L Antibody
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Metalloendopeptidase homolog PEX

 Metalloendopeptidase homolog PEX ELISA Kit
 Metalloendopeptidase homolog PEX Recombinant
 Metalloendopeptidase homolog PEX Antibody
Also known as Metalloendopeptidase homolog PEX (Phosphate regulating neutral endopeptidase) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP).
PHEX: Probably involved in bone and dentin mineralization and renal phosphate reabsorption. Defects in PHEX are a cause of hypophosphatemic rickets, X-linked dominant (XLHR). XLHR is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations inc
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lude skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood. X-linked hypophosphatemic rickets is the most common form of hypophosphatemia with an incidence of 1 in 20000. Belongs to the peptidase M13 family.

Protein type: EC 3.4.24.-; Membrane protein, integral; Protease

Cellular Component: endoplasmic reticulum; Golgi apparatus; perinuclear region of cytoplasm

Biological Process: bone mineralization; organophosphate metabolic process; proteolysis
 Phex ELISA Kit
 Phex Recombinant
 Phex Antibody
 Hyp ELISA Kit
 Hyp Recombinant
 Hyp Antibody
 Pex ELISA Kit
 Pex Recombinant
 Pex Antibody
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Metalloendopeptidase OMA1

 Metalloendopeptidase OMA1 ELISA Kit
 Metalloendopeptidase OMA1 Recombinant
 Metalloendopeptidase OMA1 Antibody
Also known as Metalloendopeptidase OMA1, mitochondrial (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog).
OMA1: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inac
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tivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Belongs to the peptidase M48 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.-; Membrane protein, integral; Membrane protein, multi-pass; Protease

Chromosomal Location of Human Ortholog: 1p32.2-p32.1

Cellular Component: mitochondrial membrane

Molecular Function: metalloendopeptidase activity

Biological Process: diet induced thermogenesis; glucose metabolic process; lipid metabolic process; misfolded or incompletely synthesized protein catabolic process; response to stress
 OMA1 ELISA Kit
 OMA1 Recombinant
 OMA1 Antibody
 MPRP1 ELISA Kit
 MPRP1 Recombinant
 MPRP1 Antibody
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