| Methanobactin mb-OB3b ELISA Kit|
Methanobactin mb-OB3b Recombinant
Methanobactin mb-OB3b Antibody
|Also known as Methanobactin mb-OB3b (Copper-binding compound) (CBC) (Hydrogen peroxide reductase) (Superoxide dismutase). |
Chalkophore involved in scavenging, uptake and suppression of toxicity of copper. Each apo-methanobactin (apo-mb) complexes 1 Cu2+ or Cu1+ ion to form Cu1+-mb (Cu-mb) which is then taken up by the cell. Enhances growth rate in the presence of copper and reduces growth lag up
on exposition to elevated levels of copper. Cu-mb contributes to the switchover from soluble methane monooxygenase (sMMO) to the membrane-bound particulate MMO (pMMO) by inducing transcription of pMMO subunit A. It also stimulates the enzymatic activity of pMMO. In the absence of copper, binds other metal ions, like Zn2+, Ag1+, Au3+, Co2+, Cd2+, Fe3+, Hg2+, Mn2+, Ni2+, Pb2+ or U6+, but not Ba2+, Ca2+, La2+, Mg2+ or Sr2+. Uptake is an active process, which may involve TonB-dependent transporters, and as such does not involve porins. Cu-Mb can be taken up by other methanotrophic bacteria but not by E.coli. Has Cu-dependent superoxide dismutase-like activity. Shows reductant-dependent oxidase and hydrogen peroxide reductase activities. Reduces copper-levels in liver in a rat model of Wilson disease.
| mbnA ELISA Kit|
| MettrDRAFT_4473 ELISA Kit|