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Microperfuranone synthase

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Microperfuranone synthase is the only protein required for the biosynthesis of the secondary metabolite microperfuranone from phenylpyruvic acid (PPA) .

Below are the list of possible Microperfuranone synthase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Microperfuranone synthase

 Microperfuranone synthase ELISA Kit
 Microperfuranone synthase Recombinant
 Microperfuranone synthase Antibody
Also known as Microperfuranone synthase (Nonribosomal peptide synthase micA).
Microperfuranone synthase is the only protein required for the biosynthesis of the secondary metabolite microperfuranone from phenylpyruvic acid (PPA) (PubMed:22627757). Several steps for the microperfuranione biosynthesis have been proposed (PubMed:22627757). These steps include the activation of PPA, by the micA ade
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nylation (A) domain to AMP-phenylpyruvic acid followed by loading of the PPA unit to the thiolation and peptide carrier (T) domain and eventually transferring to the thioesterase (TE) domain (PubMed:22627757). After loading another PPA unit onto the T domain, aldol condensation establishes the carbon-carbon bond between the alpha- and beta-carbon of the two PPA units (PubMed:22627757). Sulfur-assisted furan ring formation, TE domain mediated hydrolysis, decarboxylation, and keto-enol tautomerization would generate microperfuranone attached to the T domain (PubMed:22627757). Finally, microperfuranone is released by the TE domain (PubMed:22627757).
 micA ELISA Kit
 micA Recombinant
 micA Antibody
 AN3396 ELISA Kit
 AN3396 Recombinant
 AN3396 Antibody
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