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Mitochondrial intermembrane space import and assembly protein

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Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system. Mediates formation of disulfide bond in MICU1 in the IMS, promoting formation of the MICU1-MICU2 heterodimer that regulates mitochondrial calcium uptake.

Below are the list of possible Mitochondrial intermembrane space import and assembly protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Mitochondrial intermembrane space import and assembly protein 40

 Mitochondrial intermembrane space import and assembly protein 40 ELISA Kit
 Mitochondrial intermembrane space import and assembly protein 40 Recombinant
 Mitochondrial intermembrane space import and assembly protein 40 Antibody
Also known as Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4).
CHCHD4: Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Probably acts by forming a redox cycle with GFER/ERV1 that involves a disulfide relay system. Precursor prot
>>>
eins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (Probable). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Cellular Component: mitochondrial intermembrane space; mitochondrion

Molecular Function: protein binding; protein disulfide oxidoreductase activity

Biological Process: 'de novo' posttranslational protein folding; mitochondrial DNA repair; protein import into mitochondrial intermembrane space; protein maturation via protein folding; regulation of protein export from nucleus
 Chchd4 ELISA Kit
 Chchd4 Recombinant
 Chchd4 Antibody
 Mia40 ELISA Kit
 Mia40 Recombinant
 Mia40 Antibody
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Mitochondrial intermembrane space import and assembly protein 40 homolog

 Mitochondrial intermembrane space import and assembly protein 40 homolog ELISA Kit
 Mitochondrial intermembrane space import and assembly protein 40 homolog Recombinant
 Mitochondrial intermembrane space import and assembly protein 40 homolog Antibody
Also known as Mitochondrial intermembrane space import and assembly protein 40 homolog (AtMIA40).
Encodes Mia40, a component of the mitochondrial intermembrane space assembly machinery involved in the import pathway of the small intermembrane space proteins.
 MIA40 ELISA Kit
 MIA40 Recombinant
 MIA40 Antibody
 At5g23395 ELISA Kit
 At5g23395 Recombinant
 At5g23395 Antibody
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Mitochondrial intermembrane space import and assembly protein 40-A

 Mitochondrial intermembrane space import and assembly protein 40-A ELISA Kit
 Mitochondrial intermembrane space import and assembly protein 40-A Recombinant
 Mitochondrial intermembrane space import and assembly protein 40-A Antibody
Also known as Mitochondrial intermembrane space import and assembly protein 40-A (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-A).
Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IM
>>>
S). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.
 chchd4-a ELISA Kit
 chchd4-a Recombinant
 chchd4-a Antibody
 mia40-a ELISA Kit
 mia40-a Recombinant
 mia40-a Antibody
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Mitochondrial intermembrane space import and assembly protein 40-B

 Mitochondrial intermembrane space import and assembly protein 40-B ELISA Kit
 Mitochondrial intermembrane space import and assembly protein 40-B Recombinant
 Mitochondrial intermembrane space import and assembly protein 40-B Antibody
Also known as Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B).
Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IM
>>>
S). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.
 chchd4-b ELISA Kit
 chchd4-b Recombinant
 chchd4-b Antibody
 mia40-b ELISA Kit
 mia40-b Recombinant
 mia40-b Antibody
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