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MKL/myocardin-like protein

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Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation.

Below are the list of possible MKL/myocardin-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

MKL/myocardin-like protein 1

 MKL/myocardin-like protein 1 ELISA Kit
 MKL/myocardin-like protein 1 Recombinant
 MKL/myocardin-like protein 1 Antibody
Also known as MKL/myocardin-like protein 1 (Basic SAP coiled-coil transcription activator) (Megakaryoblastic leukemia 1 protein homolog) (Myocardin-related transcription factor A) (MRTF-A).
MKL1: Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional a
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ctivity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation. Forms with SCAI and SRF a nuclear ternary complex which binds the CArG consensus motif (CArG box) on DNA via SRF. Interacts with ACTB; interaction with ACTB prevents interaction with SCAI. Interacts with MKL2. Ubiquitously expressed, has been detected in lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, muscle, heart and brain.

Protein type: Oncoprotein; Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: actin binding; actin monomer binding; leucine zipper domain binding; protein binding; transcription coactivator activity; transcription factor activity

Biological Process: actin cytoskeleton organization and biogenesis; forebrain development; negative regulation of caspase activity; neurite development; neuron migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; smooth muscle cell differentiation
 Mkl1 ELISA Kit
 Mkl1 Recombinant
 Mkl1 Antibody
 Bsac ELISA Kit
 Bsac Recombinant
 Bsac Antibody
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MKL/myocardin-like protein 2

 MKL/myocardin-like protein 2 ELISA Kit
 MKL/myocardin-like protein 2 Recombinant
 MKL/myocardin-like protein 2 Antibody
Also known as MKL/myocardin-like protein 2 (Megakaryoblastic leukemia 2) (Myocardin-related transcription factor B) (MRTF-B).
Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
 MKL2 ELISA Kit
 MKL2 Recombinant
 MKL2 Antibody
 KIAA1243 ELISA Kit
 KIAA1243 Recombinant
 KIAA1243 Antibody
 MRTFB ELISA Kit
 MRTFB Recombinant
 MRTFB Antibody
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