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MOB kinase activator

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Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.

Below are the list of possible MOB kinase activator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

MOB kinase activator 1A

 MOB kinase activator 1A ELISA Kit
 MOB kinase activator 1A Recombinant
 MOB kinase activator 1A Antibody
Also known as MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B).
MOB1A: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
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Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38. Binds STK38 and STK38L. Interacts with LATS1 and LATS2. Forms a tripartite complex with STK38 and STK3/MST2. Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver. Belongs to the MOB1/phocein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 2p13.1

Cellular Component: cytosol

Molecular Function: protein binding
 MOB1A ELISA Kit
 MOB1A Recombinant
 MOB1A Antibody
 C2orf6 ELISA Kit
 C2orf6 Recombinant
 C2orf6 Antibody
 MOB4B ELISA Kit
 MOB4B Recombinant
 MOB4B Antibody
 MOBK1B ELISA Kit
 MOBK1B Recombinant
 MOBK1B Antibody
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MOB kinase activator 1B

 MOB kinase activator 1B ELISA Kit
 MOB kinase activator 1B Recombinant
 MOB kinase activator 1B Antibody
Also known as MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A).
MOB1B: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phos
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phorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L. Binds STK38L. Interacts with LATS1 and LATS2. Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver. Belongs to the MOB1/phocein family.

Protein type: Activator; Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: kinase activator activity; kinase binding; protein binding

Biological Process: regulation of protein amino acid autophosphorylation
 MOB1B ELISA Kit
 MOB1B Recombinant
 MOB1B Antibody
 MOB4A ELISA Kit
 MOB4A Recombinant
 MOB4A Antibody
 MOBKL1A ELISA Kit
 MOBKL1A Recombinant
 MOBKL1A Antibody
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MOB kinase activator 2

 MOB kinase activator 2 ELISA Kit
 MOB kinase activator 2 Recombinant
 MOB kinase activator 2 Antibody
Also known as MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2).
HCCA2: Stimulates the autophosphorylation and kinase activity of STK38 and STK38L. Belongs to the MOB1/phocein family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; nucleolus; nu
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cleus
 MOB2 ELISA Kit
 MOB2 Recombinant
 MOB2 Antibody
 HCCA2 ELISA Kit
 HCCA2 Recombinant
 HCCA2 Antibody
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MOB kinase activator 3A

 MOB kinase activator 3A ELISA Kit
 MOB kinase activator 3A Recombinant
 MOB kinase activator 3A Antibody
Also known as MOB kinase activator 3A (Mob1 homolog 2A) (Mps one binder kinase activator-like 2A).
May regulate the activity of kinases.
 MOB3A ELISA Kit
 MOB3A Recombinant
 MOB3A Antibody
 MOBKL2A ELISA Kit
 MOBKL2A Recombinant
 MOBKL2A Antibody
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MOB kinase activator 3B

 MOB kinase activator 3B ELISA Kit
 MOB kinase activator 3B Recombinant
 MOB kinase activator 3B Antibody
Also known as MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B).
MOBKL2B: May regulate the activity of kinases. Belongs to the MOB1/phocein family.

Chromosomal Location of Human Ortholog: 9p21.2

Molecular Function: protein binding
 MOB3B ELISA Kit
 MOB3B Recombinant
 MOB3B Antibody
 MOBKL2B ELISA Kit
 MOBKL2B Recombinant
 MOBKL2B Antibody
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MOB kinase activator 3C

 MOB kinase activator 3C ELISA Kit
 MOB kinase activator 3C Recombinant
 MOB kinase activator 3C Antibody
Also known as MOB kinase activator 3C (Mob1 homolog 2C) (Mps one binder kinase activator-like 2C).
MOBKL2C: May regulate the activity of kinases. Belongs to the MOB1/phocein family.

Chromosomal Location of Human Ortholog: 1p33

Molecular Function: protein binding
 MOB3C ELISA Kit
 MOB3C Recombinant
 MOB3C Antibody
 MOBKL2C ELISA Kit
 MOBKL2C Recombinant
 MOBKL2C Antibody
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MOB kinase activator-like 1

 MOB kinase activator-like 1 ELISA Kit
 MOB kinase activator-like 1 Recombinant
 MOB kinase activator-like 1 Antibody
Also known as MOB kinase activator-like 1 (Mob as tumor suppressor protein 1) (Dmob1) (Mps one binder kinase activator-like 1).
Coactivator of Warts (Wts) kinase in the Hippo/SWH (Sav/Wts/Hpo)signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a
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kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki)oncoprotein. The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam. Mats is essential for early development and is required for proper chromosomal segregation in developing embryos.
 mats ELISA Kit
 mats Recombinant
 mats Antibody
 CG13852 ELISA Kit
 CG13852 Recombinant
 CG13852 Antibody
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MOB kinase activator-like 1 homolog A

 MOB kinase activator-like 1 homolog A ELISA Kit
 MOB kinase activator-like 1 homolog A Recombinant
 MOB kinase activator-like 1 homolog A Antibody
Also known as MOB kinase activator-like 1 homolog A (Mps one binder kinase activator-like 1 homolog A).
 mobA ELISA Kit
 mobA Recombinant
 mobA Antibody
 DDB_G0278907 ELISA Kit
 DDB_G0278907 Recombinant
 DDB_G0278907 Antibody
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MOB kinase activator-like 1 homolog B

 MOB kinase activator-like 1 homolog B ELISA Kit
 MOB kinase activator-like 1 homolog B Recombinant
 MOB kinase activator-like 1 homolog B Antibody
Also known as MOB kinase activator-like 1 homolog B (Mps one binder kinase activator-like 1 homolog B).
 mobB ELISA Kit
 mobB Recombinant
 mobB Antibody
 DDB_G0292758 ELISA Kit
 DDB_G0292758 Recombinant
 DDB_G0292758 Antibody
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MOB kinase activator-like 1 homolog C

 MOB kinase activator-like 1 homolog C ELISA Kit
 MOB kinase activator-like 1 homolog C Recombinant
 MOB kinase activator-like 1 homolog C Antibody
Also known as MOB kinase activator-like 1 homolog C (Mps one binder kinase activator-like 1 homolog C).
 mobC ELISA Kit
 mobC Recombinant
 mobC Antibody
 DDB_G0293706 ELISA Kit
 DDB_G0293706 Recombinant
 DDB_G0293706 Antibody
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MOB kinase activator-like 1A

 MOB kinase activator-like 1A ELISA Kit
 MOB kinase activator-like 1A Recombinant
 MOB kinase activator-like 1A Antibody
Also known as MOB kinase activator-like 1A (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A).
Encodes a gene product involved in both sporogenesis and gametogenesis and is required for the normal progression of megasporogenesis and microsporogenesis.
 MOB1A ELISA Kit
 MOB1A Recombinant
 MOB1A Antibody
 At5g45550 ELISA Kit
 At5g45550 Recombinant
 At5g45550 Antibody
 MFC19.22 ELISA Kit
 MFC19.22 Recombinant
 MFC19.22 Antibody
Table BarTOPTable Bar
 

MOB kinase activator-like 1B

 MOB kinase activator-like 1B ELISA Kit
 MOB kinase activator-like 1B Recombinant
 MOB kinase activator-like 1B Antibody
Also known as MOB kinase activator-like 1B (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B).
 MOB1B ELISA Kit
 MOB1B Recombinant
 MOB1B Antibody
 At4g19045 ELISA Kit
 At4g19045 Recombinant
 At4g19045 Antibody
 F13C5.220 ELISA Kit
 F13C5.220 Recombinant
 F13C5.220 Antibody
 T18B16.1 ELISA Kit
 T18B16.1 Recombinant
 T18B16.1 Antibody
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MOB kinase activator-like 2

 MOB kinase activator-like 2 ELISA Kit
 MOB kinase activator-like 2 Recombinant
 MOB kinase activator-like 2 Antibody
Also known as MOB kinase activator-like 2 (Mob as tumor suppressor protein 2) (Dmob2) (Mps one binder kinase activator-like 2).
Required for the normal morphogenesis of a variety of polarized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites.
 Mob2 ELISA Kit
 Mob2 Recombinant
 Mob2 Antibody
 CG11711 ELISA Kit
 CG11711 Recombinant
 CG11711 Antibody
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MOB kinase activator-like 2A

 MOB kinase activator-like 2A ELISA Kit
 MOB kinase activator-like 2A Recombinant
 MOB kinase activator-like 2A Antibody
Also known as MOB kinase activator-like 2A (Mob1 homolog 2A) (Mps one binder kinase activator-like 2A).
 MOB2A ELISA Kit
 MOB2A Recombinant
 MOB2A Antibody
 At5g20440 ELISA Kit
 At5g20440 Recombinant
 At5g20440 Antibody
 F7C8.30 ELISA Kit
 F7C8.30 Recombinant
 F7C8.30 Antibody
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MOB kinase activator-like 3

 MOB kinase activator-like 3 ELISA Kit
 MOB kinase activator-like 3 Recombinant
 MOB kinase activator-like 3 Antibody
Also known as MOB kinase activator-like 3 (Mob as tumor suppressor protein 3) (Dmob3) (Mps one binder kinase activator-like 3).
 Mob3 ELISA Kit
 Mob3 Recombinant
 Mob3 Antibody
 CG4946 ELISA Kit
 CG4946 Recombinant
 CG4946 Antibody
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MOB kinase activator-like 4

 MOB kinase activator-like 4 ELISA Kit
 MOB kinase activator-like 4 Recombinant
 MOB kinase activator-like 4 Antibody
Also known as MOB kinase activator-like 4 (Mob as tumor suppressor protein 4) (Dmob4) (Mps one binder kinase activator-like 4).
 Mob4 ELISA Kit
 Mob4 Recombinant
 Mob4 Antibody
 CG3403 ELISA Kit
 CG3403 Recombinant
 CG3403 Antibody
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