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Monocarboxylate transporter

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Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis (By similarity).

Below are the list of possible Monocarboxylate transporter products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Monocarboxylate transporter 1

 Monocarboxylate transporter 1 ELISA Kit
 Monocarboxylate transporter 1 Recombinant
 Monocarboxylate transporter 1 Antibody
Also known as Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on th
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e tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis ().
 SLC16A1 ELISA Kit
 SLC16A1 Recombinant
 SLC16A1 Antibody
 MCT1 ELISA Kit
 MCT1 Recombinant
 MCT1 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 10

 Monocarboxylate transporter 10 ELISA Kit
 Monocarboxylate transporter 10 Recombinant
 Monocarboxylate transporter 10 Antibody
Also known as Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1).
SLC16A10: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: integral to memb
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rane

Molecular Function: transporter activity
 Slc16a10 ELISA Kit
 Slc16a10 Recombinant
 Slc16a10 Antibody
 Mct10 ELISA Kit
 Mct10 Recombinant
 Mct10 Antibody
 Tat1 ELISA Kit
 Tat1 Recombinant
 Tat1 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 11

 Monocarboxylate transporter 11 ELISA Kit
 Monocarboxylate transporter 11 Recombinant
 Monocarboxylate transporter 11 Antibody
Also known as Monocarboxylate transporter 11 (MCT 11) (Solute carrier family 16 member 11).
SLC16A11: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass;
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Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane

Molecular Function: lactate transmembrane transporter activity

Biological Process: lipid metabolic process
 SLC16A11 ELISA Kit
 SLC16A11 Recombinant
 SLC16A11 Antibody
 MCT11 ELISA Kit
 MCT11 Recombinant
 MCT11 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 12

 Monocarboxylate transporter 12 ELISA Kit
 Monocarboxylate transporter 12 Recombinant
 Monocarboxylate transporter 12 Antibody
Also known as Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12).
SLC16A12: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG). Renal glucosuria is defined by elevated gluc
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ose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 10q23.31

Cellular Component: integral to plasma membrane

Molecular Function: creatine transporter activity; lactate transmembrane transporter activity

Disease: Cataract, Juvenile, With Microcornea And Glucosuria
 SLC16A12 ELISA Kit
 SLC16A12 Recombinant
 SLC16A12 Antibody
 MCT12 ELISA Kit
 MCT12 Recombinant
 MCT12 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 12-B

 Monocarboxylate transporter 12-B ELISA Kit
 Monocarboxylate transporter 12-B Recombinant
 Monocarboxylate transporter 12-B Antibody
Also known as Monocarboxylate transporter 12-B (MCT 12-B) (Solute carrier family 16 member 12-B).
Proton-linked monocarboxylate transporter that mediates creatine transport across the plasma membrane.
 slc16a12b ELISA Kit
 slc16a12b Recombinant
 slc16a12b Antibody
 slc16a12 ELISA Kit
 slc16a12 Recombinant
 slc16a12 Antibody
 zgc:110441 ELISA Kit
 zgc:110441 Recombinant
 zgc:110441 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 13

 Monocarboxylate transporter 13 ELISA Kit
 Monocarboxylate transporter 13 Recombinant
 Monocarboxylate transporter 13 Antibody
Also known as Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13).
SLC16A13: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass<
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br>
Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: Golgi apparatus; integral to plasma membrane

Molecular Function: lactate transmembrane transporter activity
 SLC16A13 ELISA Kit
 SLC16A13 Recombinant
 SLC16A13 Antibody
 MCT13 ELISA Kit
 MCT13 Recombinant
 MCT13 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 14

 Monocarboxylate transporter 14 ELISA Kit
 Monocarboxylate transporter 14 Recombinant
 Monocarboxylate transporter 14 Antibody
Also known as Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14).
SLC16A14: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. 2 isoforms of the human protein are produced by alternative splicing.

P
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rotein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 2q36.3

Cellular Component: integral to membrane

Molecular Function: monocarboxylic acid transmembrane transporter activity
 SLC16A14 ELISA Kit
 SLC16A14 Recombinant
 SLC16A14 Antibody
 MCT14 ELISA Kit
 MCT14 Recombinant
 MCT14 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 2

 Monocarboxylate transporter 2 ELISA Kit
 Monocarboxylate transporter 2 Recombinant
 Monocarboxylate transporter 2 Antibody
Also known as Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7).
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as hi
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gh-affinity pyruvate transporter ().
 SLC16A7 ELISA Kit
 SLC16A7 Recombinant
 SLC16A7 Antibody
 MCT2 ELISA Kit
 MCT2 Recombinant
 MCT2 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 3

 Monocarboxylate transporter 3 ELISA Kit
 Monocarboxylate transporter 3 Recombinant
 Monocarboxylate transporter 3 Antibody
Also known as Monocarboxylate transporter 3 (MCT 3) (Proton-coupled monocarboxylate transporter 3) (Solute carrier family 16 member 8).
SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoace
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tate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: basal plasma membrane; integral to plasma membrane

Molecular Function: lactate transmembrane transporter activity
 Slc16a8 ELISA Kit
 Slc16a8 Recombinant
 Slc16a8 Antibody
 Mct3 ELISA Kit
 Mct3 Recombinant
 Mct3 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 4

 Monocarboxylate transporter 4 ELISA Kit
 Monocarboxylate transporter 4 Recombinant
 Monocarboxylate transporter 4 Antibody
Also known as Monocarboxylate transporter 4 (MCT 4) (Monocarboxylate transporter 3) (MCT 3) (Solute carrier family 16 member 3).
monocarboxylate transporter; mediates efflux of glycolytically derived lactic acid from white skeletal muscle [RGD, Feb 2006]
 Slc16a3 ELISA Kit
 Slc16a3 Recombinant
 Slc16a3 Antibody
 Mct3 ELISA Kit
 Mct3 Recombinant
 Mct3 Antibody
 Mct4 ELISA Kit
 Mct4 Recombinant
 Mct4 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 5

 Monocarboxylate transporter 5 ELISA Kit
 Monocarboxylate transporter 5 Recombinant
 Monocarboxylate transporter 5 Antibody
Also known as Monocarboxylate transporter 5 (MCT 5).
SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamil
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y. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: integral to plasma membrane

Molecular Function: lactate transmembrane transporter activity
 Slc16a4 ELISA Kit
 Slc16a4 Recombinant
 Slc16a4 Antibody
 Mct5 ELISA Kit
 Mct5 Recombinant
 Mct5 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 6

 Monocarboxylate transporter 6 ELISA Kit
 Monocarboxylate transporter 6 Recombinant
 Monocarboxylate transporter 6 Antibody
Also known as Monocarboxylate transporter 6 (MCT 6) (Monocarboxylate transporter 5) (MCT 5) (Solute carrier family 16 member 5).
SLC16A5: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pas
>>>
s

Cellular Component: integral to plasma membrane

Molecular Function: lactate transmembrane transporter activity
 Slc16a5 ELISA Kit
 Slc16a5 Recombinant
 Slc16a5 Antibody
 Mct5 ELISA Kit
 Mct5 Recombinant
 Mct5 Antibody
 Mct6 ELISA Kit
 Mct6 Recombinant
 Mct6 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 7

 Monocarboxylate transporter 7 ELISA Kit
 Monocarboxylate transporter 7 Recombinant
 Monocarboxylate transporter 7 Antibody
Also known as Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6).
SLC16A6: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pas
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s; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: integral to plasma membrane; membrane

Molecular Function: lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity

Biological Process: monocarboxylic acid transport
 SLC16A6 ELISA Kit
 SLC16A6 Recombinant
 SLC16A6 Antibody
 MCT6 ELISA Kit
 MCT6 Recombinant
 MCT6 Antibody
 MCT7 ELISA Kit
 MCT7 Recombinant
 MCT7 Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 8

 Monocarboxylate transporter 8 ELISA Kit
 Monocarboxylate transporter 8 Recombinant
 Monocarboxylate transporter 8 Antibody
Also known as Monocarboxylate transporter 8 (MCT 8) (Monocarboxylate transporter 7) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).
SLC16A2: Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr. Defects in SLC16A2 are the cause of monocarboxylate transporter 8 deficiency (MCT8 deficiency); also known as Allan-Herndon-Dudley syndrome (AHDS). MCT8 deficiency consists of a severe form of X-linked psy
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chomotor retardation combined with abnormal thyroid hormone (TH) levels. Thyroid hormone deficiency can be caused by defects of hormone synthesis and action, but it has also been linked to a defect in cellular hormone transport. Affected patients are males with abnormal relative concentrations of three circulating iodothyronines, as well as severe neurological abnormalities, including global developmental delay, central hypotonia, spastic quadriplegia, dystonic movements, rotary nystagmus, and impaired gaze and hearing. Heterozygous females had a milder thyroid phenotype and no neurological defects. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: Xq13.2

Cellular Component: integral to plasma membrane

Molecular Function: monocarboxylic acid transmembrane transporter activity; thyroid hormone transmembrane transporter activity; transporter activity

Biological Process: monocarboxylic acid transport; transport

Disease: Allan-herndon-dudley Syndrome
 SLC16A2 ELISA Kit
 SLC16A2 Recombinant
 SLC16A2 Antibody
 MCT8 ELISA Kit
 MCT8 Recombinant
 MCT8 Antibody
 XPCT ELISA Kit
 XPCT Recombinant
 XPCT Antibody
Table BarTOPTable Bar
 

Monocarboxylate transporter 9

 Monocarboxylate transporter 9 ELISA Kit
 Monocarboxylate transporter 9 Recombinant
 Monocarboxylate transporter 9 Antibody
Also known as Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9).
SLC16A9: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q21.2

Cellular Component: integral to membrane

Molecular Function: monocarboxylic acid transmembrane transporter activity; protein binding >>>
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Biological Process: urate metabolic process
 SLC16A9 ELISA Kit
 SLC16A9 Recombinant
 SLC16A9 Antibody
 C10orf36 ELISA Kit
 C10orf36 Recombinant
 C10orf36 Antibody
 MCT9 ELISA Kit
 MCT9 Recombinant
 MCT9 Antibody
Table BarTOPTable Bar
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