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mRNA export factor

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Multifunctional regulator of the expression of viral genes that contributes to the shutoff of host protein synthesis and mediates nuclear export of viral intronless mRNAs. Early in infection, this immediate early (EI) protein mediates the inhibition of cellular splicing. This results in the accumulation of unprocessed 3'end pre-mRNAs which can't be exported from the nucleus. Cellular protein synthesis is thereby shut off early after virus infection. Later in the infection, it helps recruit cellular RNA polymerase II to viral replication sites and promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP. ICP27 binds to NUP62 which may provide facilitated viral mRNA export and may compete with some host cell transport receptors for binding and inhibit cellular nucleocytoplasmic transport pathways. Also stimulates translation of viral transcripts. Repression of host gene expression blocks the cell cycle at the G1 phase and prevents apoptosis. Seems to silence the 3' splice site of the promyelocytic leukemia (PML) intron 7a, thereby switching PML isoforms from PML-II to PML-V. This could be linked to the accelerated mRNA export induced by ICP27 which might not provide sufficient time for PML pre-mRNA to be spliced in the nucleus (By similarity).

Below are the list of possible mRNA export factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

mRNA export factor

 mRNA export factor ELISA Kit
 mRNA export factor Recombinant
 mRNA export factor Antibody
Also known as mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27).
Multifunctional regulator of the expression of viral genes that contributes to the shutoff of host protein synthesis and mediates nuclear export of viral intronless mRNAs. Early in infection, this immediate early (EI) protein mediates the inhibition of cellular splicing. This results in the accum
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ulation of unprocessed 3'end pre-mRNAs which can't be exported from the nucleus. Cellular protein synthesis is thereby shut off early after virus infection. Later in the infection, it helps recruit cellular RNA polymerase II to viral replication sites and promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP. ICP27 binds to NUP62 which may provide facilitated viral mRNA export and may compete with some host cell transport receptors for binding and inhibit cellular nucleocytoplasmic transport pathways. Also stimulates translation of viral transcripts. Repression of host gene expression blocks the cell cycle at the G1 phase and prevents apoptosis. Seems to silence the 3' splice site of the promyelocytic leukemia (PML) intron 7a, thereby switching PML isoforms from PML-II to PML-V. This could be linked to the accelerated mRNA export induced by ICP27 which might not provide sufficient time for PML pre-mRNA to be spliced in the nucleus ().
 UL54 ELISA Kit
 UL54 Recombinant
 UL54 Antibody
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mRNA export factor crp79

 mRNA export factor crp79 ELISA Kit
 mRNA export factor crp79 Recombinant
 mRNA export factor crp79 Antibody
Also known as mRNA export factor crp79 (Meiotic expression up-regulated protein 5) (Polyadenylate-binding protein crp79) (PABP) (Poly(A)-binding protein).
Binds the poly(A) tail of mRNA. Involved in the export of mRNA from the nucleus to the cytoplasm.
 crp79 ELISA Kit
 crp79 Recombinant
 crp79 Antibody
 meu5 ELISA Kit
 meu5 Recombinant
 meu5 Antibody
 SPAC1610.03c ELISA Kit
 SPAC1610.03c Recombinant
 SPAC1610.03c Antibody
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mRNA export factor dss1

 mRNA export factor dss1 ELISA Kit
 mRNA export factor dss1 Recombinant
 mRNA export factor dss1 Antibody
Has a role in the mRNA export process. Links the mRNA adapter mlo3 to rae1 for targeting mRNA-protein complex to the proteins of the nucleoporin complex (NPC).
 dss1 ELISA Kit
 dss1 Recombinant
 dss1 Antibody
 SPAC3G6.02 ELISA Kit
 SPAC3G6.02 Recombinant
 SPAC3G6.02 Antibody
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mRNA export factor elf1

 mRNA export factor elf1 ELISA Kit
 mRNA export factor elf1 Recombinant
 mRNA export factor elf1 Antibody
Has a direct role in the mRNA export process. Appears to act within the rae1 mediated mRNA export pathway.
 elf1 ELISA Kit
 elf1 Recombinant
 elf1 Antibody
 SPAC3C7.08c ELISA Kit
 SPAC3C7.08c Recombinant
 SPAC3C7.08c Antibody
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mRNA export factor ICP27 homolog

 mRNA export factor ICP27 homolog ELISA Kit
 mRNA export factor ICP27 homolog Recombinant
 mRNA export factor ICP27 homolog Antibody
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs.
 KA3L ELISA Kit
 KA3L Recombinant
 KA3L Antibody
 U42 ELISA Kit
 U42 Recombinant
 U42 Antibody
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mRNA export factor MEX67

 mRNA export factor MEX67 ELISA Kit
 mRNA export factor MEX67 Recombinant
 mRNA export factor MEX67 Antibody
Involved in the export of mRNA from the nucleus to the cytoplasm.
 MEX67 ELISA Kit
 MEX67 Recombinant
 MEX67 Antibody
 YPL169C ELISA Kit
 YPL169C Recombinant
 YPL169C Antibody
 P2520 ELISA Kit
 P2520 Recombinant
 P2520 Antibody
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mRNA export factor rae-1

 mRNA export factor rae-1 ELISA Kit
 mRNA export factor rae-1 Recombinant
 mRNA export factor rae-1 Antibody
Also known as mRNA export factor rae-1 (Nuclear pore complex protein 17) (Nucleoporin-17).
Functions as a component of the nuclear pore complex (NPC) (PubMed:12937276). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (). It is specifically important for nuclear mRNA export (PubMed:12937276). Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral mic
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rotubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons (PubMed:22357847).
 rae-1 ELISA Kit
 rae-1 Recombinant
 rae-1 Antibody
 npp-17 ELISA Kit
 npp-17 Recombinant
 npp-17 Antibody
 F10G8.3 ELISA Kit
 F10G8.3 Recombinant
 F10G8.3 Antibody
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mRNA export factor rsm1

 mRNA export factor rsm1 ELISA Kit
 mRNA export factor rsm1 Recombinant
 mRNA export factor rsm1 Antibody
Involved in the export of mRNA from the nucleus to the cytoplasm.
 rsm1 ELISA Kit
 rsm1 Recombinant
 rsm1 Antibody
 SPCC1753.05 ELISA Kit
 SPCC1753.05 Recombinant
 SPCC1753.05 Antibody
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