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Mucosal addressin cell adhesion molecule

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Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Below are the list of possible Mucosal addressin cell adhesion molecule products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Mucosal addressin cell adhesion molecule 1

 Mucosal addressin cell adhesion molecule 1 ELISA Kit
 Mucosal addressin cell adhesion molecule 1 Recombinant
 Mucosal addressin cell adhesion molecule 1 Antibody
Also known as Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (hMAdCAM-1).
MADCAM1: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2,
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lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L- selectin binding. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: membrane; plasma membrane

Biological Process: cell adhesion; cell-matrix adhesion; extracellular matrix organization and biogenesis; heterotypic cell-cell adhesion; immune response; integrin-mediated signaling pathway; leukocyte tethering or rolling; positive regulation of leukocyte migration; receptor clustering; regulation of immune response; signal transduction
 MADCAM1 ELISA Kit
 MADCAM1 Recombinant
 MADCAM1 Antibody
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