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Multidrug and toxin extrusion protein

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Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Below are the list of possible Multidrug and toxin extrusion protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Multidrug and toxin extrusion protein 1

 Multidrug and toxin extrusion protein 1 ELISA Kit
 Multidrug and toxin extrusion protein 1 Recombinant
 Multidrug and toxin extrusion protein 1 Antibody
Also known as Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1).
SLC47A1: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin an
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d cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: plasma membrane

Molecular Function: drug transporter activity; drug:hydrogen antiporter activity; monovalent cation:proton antiporter activity

Biological Process: multidrug transport; organic cation transport; transmembrane transport
 SLC47A1 ELISA Kit
 SLC47A1 Recombinant
 SLC47A1 Antibody
 MATE1 ELISA Kit
 MATE1 Recombinant
 MATE1 Antibody
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Multidrug and toxin extrusion protein 2

 Multidrug and toxin extrusion protein 2 ELISA Kit
 Multidrug and toxin extrusion protein 2 Recombinant
 Multidrug and toxin extrusion protein 2 Antibody
Also known as Multidrug and toxin extrusion protein 2 (MATE-2) (hMATE-2) (Kidney-specific H(+)/organic cation antiporter) (Solute carrier family 47 member 2).
SLC47A2: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Respon
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sible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: plasma membrane

Molecular Function: drug transporter activity; drug:hydrogen antiporter activity

Biological Process: multidrug transport; transmembrane transport
 SLC47A2 ELISA Kit
 SLC47A2 Recombinant
 SLC47A2 Antibody
 MATE2 ELISA Kit
 MATE2 Recombinant
 MATE2 Antibody
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