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Multifunctional-autoprocessing repeats-in-toxin

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Multifunctional-autoprocessing repeats-in-toxin: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm .

Below are the list of possible Multifunctional-autoprocessing repeats-in-toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Multifunctional-autoprocessing repeats-in-toxin

 Multifunctional-autoprocessing repeats-in-toxin ELISA Kit
 Multifunctional-autoprocessing repeats-in-toxin Recombinant
 Multifunctional-autoprocessing repeats-in-toxin Antibody
Also known as Multifunctional-autoprocessing repeats-in-toxin (MARTX).
Multifunctional-autoprocessing repeats-in-toxin: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm (PubMed:26185092). Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers
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the Cysteine protease domain-containing toxin F3 chain to the host cytosol (PubMed:17464284, PubMed:18591243, PubMed:18845756, PubMed:19620709, PubMed:19465933). The Cysteine protease domain-containing toxin F3 chain will then further cleave and release effector toxin chains that cause disassembly of the actin cytoskeleton and enhance V.cholerae colonization of the small intestine, possibly by facilitating evasion of phagocytic cells (PubMed:11553575, PubMed:12045243, PubMed:17698573, PubMed:17698571, PubMed:19812690, PubMed:19620709).
 rtxA ELISA Kit
 rtxA Recombinant
 rtxA Antibody
 rtx ELISA Kit
 rtx Recombinant
 rtx Antibody
 VC_1451 ELISA Kit
 VC_1451 Recombinant
 VC_1451 Antibody
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