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Multiple epidermal growth factor-like domains protein

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Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation probably through regulation of the notch signaling pathway.

Below are the list of possible Multiple epidermal growth factor-like domains protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Multiple epidermal growth factor-like domains protein 10

 Multiple epidermal growth factor-like domains protein 10 ELISA Kit
 Multiple epidermal growth factor-like domains protein 10 Recombinant
 Multiple epidermal growth factor-like domains protein 10 Antibody
Also known as Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10).
MEGF10: Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the
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mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation problably through regulation of the notch signaling pathway. Defects in MEGF10 are the cause of myopathy, early-onset, areflexia, respiratory distress, and dysphagia (EMARDD). An autosomal recessive congenital myopathy characterized by onset at birth, or early in infancy, of respiratory distress caused by diaphragmatic weakness. Additional features are dysphagia resulting in poor feeding, failure to thrive, poor head control, facial weakness, cleft palate, contractures and scoliosis. Affected individuals become ventilator-dependent, and most require feeding by gastrostomy. The disorder results in severe muscle weakness and most patients never achieve walking. Death from respiratory failure in childhood occurs in about half of patients. Muscle biopsy shows myopathic changes, replacement of myofibers with fatty tissue, small and incompletely fused muscle fibers, and variation in fiber size. Short regions of sarcomeric disorganization with few or no mitochondria (minicores) have been observed in some cases. Belongs to the MEGF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: phagocytic cup

Molecular Function: complement component C1q binding; scavenger receptor activity

Biological Process: engulfment of apoptotic cell; homotypic cell-cell adhesion; muscle cell development; recognition of apoptotic cell; regulation of muscle cell differentiation; regulation of skeletal muscle development; satellite cell activation; satellite cell differentiation; satellite cell proliferation
 Megf10 ELISA Kit
 Megf10 Recombinant
 Megf10 Antibody
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Multiple epidermal growth factor-like domains protein 11

 Multiple epidermal growth factor-like domains protein 11 ELISA Kit
 Multiple epidermal growth factor-like domains protein 11 Recombinant
 Multiple epidermal growth factor-like domains protein 11 Antibody
Also known as Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11).
MEGF11: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. Belongs to the MEGF family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human
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Ortholog: 15q22.31

Biological Process: homotypic cell-cell adhesion
 MEGF11 ELISA Kit
 MEGF11 Recombinant
 MEGF11 Antibody
 KIAA1781 ELISA Kit
 KIAA1781 Recombinant
 KIAA1781 Antibody
 UNQ1949/PRO4432 ELISA Kit
 UNQ1949/PRO4432 Recombinant
 UNQ1949/PRO4432 Antibody
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Multiple epidermal growth factor-like domains protein 6

 Multiple epidermal growth factor-like domains protein 6 ELISA Kit
 Multiple epidermal growth factor-like domains protein 6 Recombinant
 Multiple epidermal growth factor-like domains protein 6 Antibody
Also known as Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3).
MEGF6: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Secreted; Secreted, signal peptide
 Megf6 ELISA Kit
 Megf6 Recombinant
 Megf6 Antibody
 Egfl3 ELISA Kit
 Egfl3 Recombinant
 Egfl3 Antibody
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Multiple epidermal growth factor-like domains protein 8

 Multiple epidermal growth factor-like domains protein 8 ELISA Kit
 Multiple epidermal growth factor-like domains protein 8 Recombinant
 Multiple epidermal growth factor-like domains protein 8 Antibody
Also known as Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4).
MEGF8: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; nucleus

Biological Process: BMP signaling pathway; cell m
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igration involved in gastrulation; determination of left/right symmetry; embryonic limb morphogenesis; embryonic skeletal morphogenesis; epiboly involved in gastrulation with mouth forming second; limb morphogenesis; positive regulation of axon extension involved in axon guidance; regulation of gene expression
 Megf8 ELISA Kit
 Megf8 Recombinant
 Megf8 Antibody
 Egfl4 ELISA Kit
 Egfl4 Recombinant
 Egfl4 Antibody
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Multiple epidermal growth factor-like domains protein 9

 Multiple epidermal growth factor-like domains protein 9 ELISA Kit
 Multiple epidermal growth factor-like domains protein 9 Recombinant
 Multiple epidermal growth factor-like domains protein 9 Antibody
Also known as Multiple epidermal growth factor-like domains protein 9 (Multiple EGF-like domains protein 9) (Epidermal growth factor-like protein 5) (EGF-like protein 5).
MEGF9:

Protein type: Membrane protein, integral

Cellular Component: basement membrane
 Megf9 ELISA Kit
 Megf9 Recombinant
 Megf9 Antibody
 Egfl5 ELISA Kit
 Egfl5 Recombinant
 Egfl5 Antibody
 Kiaa0818 ELISA Kit
 Kiaa0818 Recombinant
 Kiaa0818 Antibody
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