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Myc box-dependent-interacting protein

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May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.

Below are the list of possible Myc box-dependent-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Myc box-dependent-interacting protein 1

 Myc box-dependent-interacting protein 1 ELISA Kit
 Myc box-dependent-interacting protein 1 Recombinant
 Myc box-dependent-interacting protein 1 Antibody
Also known as Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1).
BIN1: May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy type 2 (CNM2). A congenital muscl
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e disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Cytoskeletal; Tumor suppressor; Vesicle

Chromosomal Location of Human Ortholog: 2q14

Cellular Component: actin cytoskeleton; axon; cytoplasm; I band; membrane; T-tubule; Z disc

Molecular Function: actin filament binding; identical protein binding; protein binding; tau protein binding

Biological Process: cell proliferation; nuclear organization and biogenesis; positive regulation of apoptosis; positive regulation of astrocyte differentiation; regulation of neuron differentiation

Disease: Myopathy, Centronuclear, 2
 BIN1 ELISA Kit
 BIN1 Recombinant
 BIN1 Antibody
 AMPHL ELISA Kit
 AMPHL Recombinant
 AMPHL Antibody
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