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N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

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Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.

Below are the list of possible N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein ELISA Kit
 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein Recombinant
 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein Antibody
Also known as N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A).
PIGA: Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH). PNH is a
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disorder characterized by hemolytic anemia with hemoglobinuria, thromboses in large vessels, and a deficiency in hematopoiesis. Clinical manifestation of red blood cell breakdown with release of hemoglobin into the urine is manifested most prominently by dark-colored urine in the morning. Defects in PIGA are the cause of multiple congenital anomalies-hypotonia-seizures syndrome type 2 (MCAHS2). An X-linked recessive developmental disorder characterized by dysmorphic features, neonatal hypotonia, myoclonic seizures, and variable congenital anomalies involving the central nervous, cardiac, and urinary systems. Most affected individuals die in infancy. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.4.1.198; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Transferase

Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; membrane

Biological Process: GPI anchor biosynthetic process
 Piga ELISA Kit
 Piga Recombinant
 Piga Antibody
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N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1

 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 ELISA Kit
 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 Recombinant
 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 Antibody
Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.
 gpi1 ELISA Kit
 gpi1 Recombinant
 gpi1 Antibody
 SPBC30D10.11 ELISA Kit
 SPBC30D10.11 Recombinant
 SPBC30D10.11 Antibody
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