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NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase

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Component of the DprE1-DprE2 complex that catalyzes the 2-step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl-phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate channel' at the interface of DprE1-DprE2 complex. DprE2 then catalyzes the second step of epimerization, the NAD(+)-dependent reduction of DPX that leads to the formation of DPA.

Below are the list of possible NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase

 NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase ELISA Kit
 NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase Recombinant
 NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase Antibody
Also known as NAD-dependent decaprenylphosphoryl-D-2-keto erythropentose reductase (Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase) (Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase 2) (DprE2).
Dpre1 and DprE2 are involved in the epimerization of decaprenylphosphoryl-beta-D-ribofuranose (DPR) to decaprenylphosphoryl-beta-D-arabinofuranose (DPA), the arabinosyl donor fo
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r the biosynthesis of mycobacterial cell wall arabinan polymers. The reaction proceeds via the keto intermediate decaprenylphosphoryl-D-2-keto-erythro-pentofuranose (DPX). DprE2 catalyzes the NAD-dependent reduction at the C-2 of DPX to yield DPA.
 dprE2 ELISA Kit
 dprE2 Recombinant
 dprE2 Antibody
 Mb3820 ELISA Kit
 Mb3820 Recombinant
 Mb3820 Antibody
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