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NAD-dependent epimerase/dehydratase

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NAD-dependent epimerase/dehydratase; part of the gene cluster that mediates the biosynthesis of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities .

Below are the list of possible NAD-dependent epimerase/dehydratase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NAD-dependent epimerase/dehydratase terH

 NAD-dependent epimerase/dehydratase terH ELISA Kit
 NAD-dependent epimerase/dehydratase terH Recombinant
 NAD-dependent epimerase/dehydratase terH Antibody
Also known as NAD-dependent epimerase/dehydratase terH (Terrein biosynthesis cluster protein terH).
NAD-dependent epimerase/dehydratase; part of the gene cluster that mediates the biosynthesis of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities (PubMed:24816227). The first step in the pathway is performed by the polyketide synthase ter
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A that produces 4-hydroxy-6-methylpyranon (4-HMP), orsellinic acid (OA), and 2,3-dehydro-6-hydroxymellein (2,3-dehydro-6-HM) by condensing acetyl-CoA with two, three, or four malonyl-CoA units, respectively (PubMed:24816227). 4-HMP and OA are not pathway intermediates, but are rather shunt or side products (PubMed:24816227). 2,3-dehydro-6-HM is further converted to 6-hydroxymellein (6-HM) by the 6-hydroxymellein synthase terB (PubMed:24816227). The monooxygenases terC and terD, the multicopper oxidase terE and the Kelch-like protein terF are then involved in the transformation of 6-HM to terrein (PubMed:24816227). Even if they are co-regulated with the other terrein cluster genes, terH and terI seem to be dispensable for terrein production; whereas one or both of the 2 transporters terG and terJ are probably required for efficient secretion of metabolites (PubMed:24816227).
 terH ELISA Kit
 terH Recombinant
 terH Antibody
 ATEG_00137 ELISA Kit
 ATEG_00137 Recombinant
 ATEG_00137 Antibody
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