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NADPH oxidase

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Pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism.

Below are the list of possible NADPH oxidase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NADPH oxidase 1

 NADPH oxidase 1 ELISA Kit
 NADPH oxidase 1 Recombinant
 NADPH oxidase 1 Antibody
Also known as NADPH oxidase 1 (NOX-1).
NOX1: NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas N
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OH-1S does not contain an electron transport chain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, misc.; EC 1.-.-.-; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Oxidoreductase

Cellular Component: cytoplasm; early endosome; endosome; NADPH oxidase complex

Molecular Function: Rac GTPase binding; superoxide-generating NADPH oxidase activity; voltage-gated proton channel activity

Biological Process: angiogenesis; cell migration; extracellular matrix organization and biogenesis; hydrogen peroxide metabolic process; intracellular pH elevation; positive regulation of cell proliferation; positive regulation of integrin biosynthetic process; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; positive regulation of smooth muscle cell proliferation; proton transport; regulation of systemic arterial blood pressure by renin-angiotensin; response to reactive oxygen species; signal transduction; superoxide metabolic process; superoxide release
 Nox1 ELISA Kit
 Nox1 Recombinant
 Nox1 Antibody
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NADPH oxidase 3

 NADPH oxidase 3 ELISA Kit
 NADPH oxidase 3 Recombinant
 NADPH oxidase 3 Antibody
NOX3: NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.

Protein type: EC 1.6.3.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Cellular Component: cytoplasm; NADPH o
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xidase complex

Molecular Function: protein binding; superoxide-generating NADPH oxidase activity

Biological Process: detection of gravity; otolith development; response to gravity; superoxide release; thermoregulation
 Nox3 ELISA Kit
 Nox3 Recombinant
 Nox3 Antibody
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NADPH oxidase 4

 NADPH oxidase 4 ELISA Kit
 NADPH oxidase 4 Recombinant
 NADPH oxidase 4 Antibody
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediat
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ed activation of NFKB ().
 NOX4 ELISA Kit
 NOX4 Recombinant
 NOX4 Antibody
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NADPH oxidase 5

 NADPH oxidase 5 ELISA Kit
 NADPH oxidase 5 Recombinant
 NADPH oxidase 5 Antibody
NOX5: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial r
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esponse to thrombin. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.6.3.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: endoplasmic reticulum membrane

Molecular Function: hydrogen ion channel activity; superoxide-generating NADPH oxidase activity

Biological Process: endothelial cell proliferation; response to reactive oxygen species; superoxide release
 NOX5 ELISA Kit
 NOX5 Recombinant
 NOX5 Antibody
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