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NADPH oxidase organizer

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Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.

Below are the list of possible NADPH oxidase organizer products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NADPH oxidase organizer 1

 NADPH oxidase organizer 1 ELISA Kit
 NADPH oxidase organizer 1 Recombinant
 NADPH oxidase organizer 1 Antibody
Also known as NADPH oxidase organizer 1 (NADPH oxidase regulatory protein) (Nox organizer 1) (Nox-organizing protein 1) (SH3 and PX domain-containing protein 5).
NOXO1: Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activi
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ty. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: intracellular; NADPH oxidase complex; plasma membrane

Molecular Function: enzyme binding; identical protein binding; phosphoinositide binding; phospholipid binding; protein binding; superoxide-generating NADPH oxidase activator activity

Biological Process: extracellular matrix disassembly; regulation of hydrogen peroxide metabolic process; superoxide metabolic process
 NOXO1 ELISA Kit
 NOXO1 Recombinant
 NOXO1 Antibody
 P41NOX ELISA Kit
 P41NOX Recombinant
 P41NOX Antibody
 SH3PXD5 ELISA Kit
 SH3PXD5 Recombinant
 SH3PXD5 Antibody
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