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Nanos

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Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES-driven, polyadenylated RNAs or nonpolyadenylated RNAs (By similarity). Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival.

Below are the list of possible Nanos products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nanos homolog 1

 Nanos homolog 1 ELISA Kit
 Nanos homolog 1 Recombinant
 Nanos homolog 1 Antibody
Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES-driven, polyadenylated RNAs or nonpolyadenylated RNAs (). Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival.
 nanos1 ELISA Kit
 nanos1 Recombinant
 nanos1 Antibody
 wu:fb76c12 ELISA Kit
 wu:fb76c12 Recombinant
 wu:fb76c12 Antibody
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Nanos homolog 2

 Nanos homolog 2 ELISA Kit
 Nanos homolog 2 Recombinant
 Nanos homolog 2 Antibody
Also known as Nanos homolog 2 (NOS-2).
NANOS2: Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replica
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tion, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state. Belongs to the nanos family.

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytoplasm; nucleus; perinuclear region of cytoplasm

Molecular Function: protein binding

Biological Process: germ-line stem cell maintenance; mRNA catabolic process; negative regulation of meiosis; negative regulation of translation; spermatogenesis
 NANOS2 ELISA Kit
 NANOS2 Recombinant
 NANOS2 Antibody
 NOS2 ELISA Kit
 NOS2 Recombinant
 NOS2 Antibody
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Nanos homolog 3

 Nanos homolog 3 ELISA Kit
 Nanos homolog 3 Recombinant
 Nanos homolog 3 Antibody
Also known as Nanos homolog 3 (NOS-3).
NANOS3: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Ess
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ential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. Belongs to the nanos family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; RNA-binding

Cellular Component: cytoplasm; nucleus; perinuclear region of cytoplasm; stress granule

Molecular Function: protein binding; RNA binding

Biological Process: germ cell development; negative regulation of translation; oogenesis; regulation of cell cycle; regulation of translation; spermatogenesis
 Nanos3 ELISA Kit
 Nanos3 Recombinant
 Nanos3 Antibody
 Nos3 ELISA Kit
 Nos3 Recombinant
 Nos3 Antibody
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