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Nascent polypeptide-associated complex

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Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). Isoform 1 and isoform 2 appear to bind DNA and play roles in transcription. Isoform 1 may function as a specific coactivator for JUN, acting to stabilize the interaction of JUN homodimers with promoter elements.

Below are the list of possible Nascent polypeptide-associated complex products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nascent polypeptide-associated complex subunit alpha

 Nascent polypeptide-associated complex subunit alpha ELISA Kit
 Nascent polypeptide-associated complex subunit alpha Recombinant
 Nascent polypeptide-associated complex subunit alpha Antibody
Also known as Nascent polypeptide-associated complex subunit alpha (Alpha-NAC) (Alpha-NAC/1.9.2).
NACA iso2: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptide
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s to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. Belongs to the NAC-alpha family. Interacts with TBP and JUN. Part of the nascent polypeptide-associated complex (NAC), consisting of NACA and BTF3. NAC associates with ribosomes through the BTF3 subunit. Both subunits can contact nascent polypeptide chains. Interacts with ASFV protein H339R.

Protein type: Motility/polarity/chemotaxis; Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleus

Molecular Function: TATA-binding protein binding; transcription coactivator activity

Biological Process: myoblast migration; positive regulation of skeletal muscle growth; regulation of skeletal muscle fiber development; skeletal muscle regeneration
 Naca ELISA Kit
 Naca Recombinant
 Naca Antibody
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Nascent polypeptide-associated complex subunit alpha, muscle-specific form

 Nascent polypeptide-associated complex subunit alpha, muscle-specific form ELISA Kit
 Nascent polypeptide-associated complex subunit alpha, muscle-specific form Recombinant
 Nascent polypeptide-associated complex subunit alpha, muscle-specific form Antibody
Also known as Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form) (skNAC).
NACA: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targ
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ets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. Belongs to the NAC-alpha family. Interacts with TBP and JUN. Part of the nascent polypeptide-associated complex (NAC), consisting of NACA and BTF3. NAC associates with ribosomes through the BTF3 subunit. Both subunits can contact nascent polypeptide chains. Interacts with ASFV protein H339R.

Protein type: Motility/polarity/chemotaxis; Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleus

Molecular Function: TATA-binding protein binding; transcription coactivator activity

Biological Process: myoblast migration; positive regulation of skeletal muscle growth; regulation of skeletal muscle fiber development; skeletal muscle regeneration
 Naca ELISA Kit
 Naca Recombinant
 Naca Antibody
 Gm1878 ELISA Kit
 Gm1878 Recombinant
 Gm1878 Antibody
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Nascent polypeptide-associated complex subunit alpha-2

 Nascent polypeptide-associated complex subunit alpha-2 ELISA Kit
 Nascent polypeptide-associated complex subunit alpha-2 Recombinant
 Nascent polypeptide-associated complex subunit alpha-2 Antibody
Also known as Nascent polypeptide-associated complex subunit alpha-2 (Alpha-NAC-like) (Hom s 2.01) (Nascent polypeptide-associated complex subunit alpha-like) (NAC-alpha-like).
NACA2: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal r
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ecognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). Belongs to the NAC-alpha family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q23.2
 NACA2 ELISA Kit
 NACA2 Recombinant
 NACA2 Antibody
 NACAL ELISA Kit
 NACAL Recombinant
 NACAL Antibody
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Nascent polypeptide-associated complex subunit beta

 Nascent polypeptide-associated complex subunit beta ELISA Kit
 Nascent polypeptide-associated complex subunit beta Recombinant
 Nascent polypeptide-associated complex subunit beta Antibody
 At1g73230 ELISA Kit
 At1g73230 Recombinant
 At1g73230 Antibody
 T18K17.10 ELISA Kit
 T18K17.10 Recombinant
 T18K17.10 Antibody
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Nascent polypeptide-associated complex subunit beta-1

 Nascent polypeptide-associated complex subunit beta-1 ELISA Kit
 Nascent polypeptide-associated complex subunit beta-1 Recombinant
 Nascent polypeptide-associated complex subunit beta-1 Antibody
Also known as Nascent polypeptide-associated complex subunit beta-1 (NAC-beta-1) (BTF3 homolog EGD1) (Beta-1-NAC) (GAL4 DNA-binding enhancer protein 1).
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeti
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ng. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
 EGD1 ELISA Kit
 EGD1 Recombinant
 EGD1 Antibody
 SCY_5688 ELISA Kit
 SCY_5688 Recombinant
 SCY_5688 Antibody
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Nascent polypeptide-associated complex subunit beta-2

 Nascent polypeptide-associated complex subunit beta-2 ELISA Kit
 Nascent polypeptide-associated complex subunit beta-2 Recombinant
 Nascent polypeptide-associated complex subunit beta-2 Antibody
Also known as Nascent polypeptide-associated complex subunit beta-2 (NAC-beta-2) (BTF3 homolog BTT1) (Beta-2-NAC).
Acts as component of the nascent polypeptide-associated complex (NAC), which promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane. Also blocks the inappropriate interaction of ribosomes translating non-secretory n
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ascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. BTT1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II ().
 BTT1 ELISA Kit
 BTT1 Recombinant
 BTT1 Antibody
 SCY_1142 ELISA Kit
 SCY_1142 Recombinant
 SCY_1142 Antibody
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