| Natural cytotoxicity triggering receptor 3 ELISA Kit|
Natural cytotoxicity triggering receptor 3 Recombinant
Natural cytotoxicity triggering receptor 3 Antibody
|Also known as Natural cytotoxicity triggering receptor 3 (Activating natural killer receptor p30) (Natural killer cell p30-related protein) (NK-p30) (NKp30) (CD antigen CD337). |
NCR3: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation. Belongs to the natural cytotoxicity
receptor (NCR) family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: cell-cell adherens junction; integral to plasma membrane; plasma membrane
Molecular Function: cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding
Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; regulation of immune response; susceptibility to natural killer cell mediated cytotoxicity
Disease: Malaria, Mild, Susceptibility To
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