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Natural killer cell receptor

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Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor .

Below are the list of possible Natural killer cell receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Natural killer cell receptor 2B4

 Natural killer cell receptor 2B4 ELISA Kit
 Natural killer cell receptor 2B4 Recombinant
 Natural killer cell receptor 2B4 Antibody
Also known as Natural killer cell receptor 2B4 (NK cell activation-inducing ligand) (NAIL) (NK cell type I receptor protein 2B4) (NKR2B4) (h2B4) (SLAM family member 4) (SLAMF4) (Signaling lymphocytic activation molecule 4) (CD antigen CD244).
CD244: Modulate other receptor-ligand interactions to enhance leukocyte activation. 4 isoforms of the human protein are produced by alternative splicing.<
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Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: external side of plasma membrane; plasma membrane

Molecular Function: MHC class I protein binding; protein binding

Biological Process: leukocyte migration; natural killer cell activation during immune response; signal transduction

Disease: Rheumatoid Arthritis
 CD244 ELISA Kit
 CD244 Recombinant
 CD244 Antibody
 2B4 ELISA Kit
 2B4 Recombinant
 2B4 Antibody
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