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Nck-associated protein

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Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 (By similarity).

Below are the list of possible Nck-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nck-associated protein 1

 Nck-associated protein 1 ELISA Kit
 Nck-associated protein 1 Recombinant
 Nck-associated protein 1 Antibody
Also known as Nck-associated protein 1 (NAP 1).
Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 ().
 nckap1 ELISA Kit
 nckap1 Recombinant
 nckap1 Antibody
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Nck-associated protein 1 homolog

 Nck-associated protein 1 homolog ELISA Kit
 Nck-associated protein 1 homolog Recombinant
 Nck-associated protein 1 homolog Antibody
Involved in regulation of actin and microtubule organization. Involved in cell adhesion.
 napA ELISA Kit
 napA Recombinant
 napA Antibody
 nap1 ELISA Kit
 nap1 Recombinant
 nap1 Antibody
 DDB_G0274519 ELISA Kit
 DDB_G0274519 Recombinant
 DDB_G0274519 Antibody
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Nck-associated protein 1-like

 Nck-associated protein 1-like ELISA Kit
 Nck-associated protein 1-like Recombinant
 Nck-associated protein 1-like Antibody
Also known as Nck-associated protein 1-like (Hematopoietic protein 1) (Membrane-associated protein HEM-1).
HEM1: a component of the Scar/WAVE complex that plays an important role in regulating cell shape and motility. Found at elevated levels in cells of hematopoietic lineage. Localizes to propagating waves at the leading edge of a motile human neutrophils. The complex stimulates actin assembly
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; polymerized actin is reciprocally required to remove the complex from the membrane. Overexpression is associated with poor outcome in B-cell chronic lymphocytic leukemia patients.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: cytosol; membrane

Molecular Function: GTPase activator activity; protein binding; protein complex binding; protein kinase activator activity

Biological Process: B cell homeostasis; B cell receptor signaling pathway; chemotaxis; cortical actin cytoskeleton organization and biogenesis; erythrocyte development; maintenance of cell polarity; myeloid cell homeostasis; negative regulation of apoptosis; negative regulation of interleukin-17 production; negative regulation of interleukin-6 production; neutrophil chemotaxis; positive regulation of actin filament polymerization; positive regulation of B cell differentiation; positive regulation of B cell proliferation; positive regulation of CD4-positive, alpha beta T cell differentiation; positive regulation of CD8-positive, alpha-beta T cell differentiation; positive regulation of cell adhesion mediated by integrin; positive regulation of erythrocyte differentiation; positive regulation of gamma-delta T cell differentiation; positive regulation of lymphocyte differentiation; positive regulation of phagocytosis, engulfment; positive regulation of phosphorylation; positive regulation of T cell proliferation; protein complex assembly; response to drug; T cell homeostasis; vascular endothelial growth factor receptor signaling pathway
 NCKAP1L ELISA Kit
 NCKAP1L Recombinant
 NCKAP1L Antibody
 HEM1 ELISA Kit
 HEM1 Recombinant
 HEM1 Antibody
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Nck-associated protein 5

 Nck-associated protein 5 ELISA Kit
 Nck-associated protein 5 Recombinant
 Nck-associated protein 5 Antibody
Also known as Nck-associated protein 5 (NAP-5) (Peripheral clock protein).
NAP5: 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2q21.2
 NCKAP5 ELISA Kit
 NCKAP5 Recombinant
 NCKAP5 Antibody
 ERIH ELISA Kit
 ERIH Recombinant
 ERIH Antibody
 NAP5 ELISA Kit
 NAP5 Recombinant
 NAP5 Antibody
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Nck-associated protein 5-like

 Nck-associated protein 5-like ELISA Kit
 Nck-associated protein 5-like Recombinant
 Nck-associated protein 5-like Antibody
Also known as Nck-associated protein 5-like (Centrosomal protein of 169 kDa) (Cep169).
NCKAP5L: 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Cellular Component: centrosome

Biological Process: microtubule bundle formation; microtubule depolymerization
 Nckap5l ELISA Kit
 Nckap5l Recombinant
 Nckap5l Antibody
 Cep169 ELISA Kit
 Cep169 Recombinant
 Cep169 Antibody
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