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Nephrin

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Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.

Below are the list of possible Nephrin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nephrin

 Nephrin ELISA Kit
 Nephrin Recombinant
 Nephrin Antibody
Also known as Nephrin (Renal glomerulus-specific cell adhesion receptor).
NPHS1: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Interacts with CD2AP (via C-
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terminal domain). Interacts with MAGI1 (via PDZ 2 and 3 domains) forming a tripartite complex with IGSF5/JAM4. Interacts with DDN; the interaction is direct. Self-associates (via the Ig-like domains). Also interacts (via the Ig-like domains) with KIRREL/NEPH1 and KIRREL2; the interaction with KIRREL is dependent on KIRREL glycosylation. Forms a complex with ACTN4, CASK, IQGAP1, MAGI2, SPTAN1 and SPTBN1. Interacts with NPHS2. Specifically expressed in podocytes of kidney glomeruli. Belongs to the immunoglobulin superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral

Cellular Component: cell projection; lipid raft; membrane; plasma membrane; protein complex

Molecular Function: alpha-actinin binding; myosin binding; protein binding; protein domain specific binding; spectrin binding

Biological Process: cell adhesion; glomerular basement membrane development; glomerular filtration; JNK cascade; MAPKKK cascade; myoblast fusion; positive regulation of actin filament polymerization; skeletal muscle development
 Nphs1 ELISA Kit
 Nphs1 Recombinant
 Nphs1 Antibody
 Nphn ELISA Kit
 Nphn Recombinant
 Nphn Antibody
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