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Neuroendocrine protein

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Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Below are the list of possible Neuroendocrine protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Neuroendocrine protein 7B2

 Neuroendocrine protein 7B2 ELISA Kit
 Neuroendocrine protein 7B2 Recombinant
 Neuroendocrine protein 7B2 Antibody
Also known as Neuroendocrine protein 7B2 (Pituitary polypeptide) (Secretogranin V) (Secretogranin-5) (Secretory granule endocrine protein I).
7B2: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory
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pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. Belongs to the 7B2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 15q13-q14

Cellular Component: secretory granule

Molecular Function: enzyme inhibitor activity; GTP binding; protein binding; unfolded protein binding

Biological Process: intracellular protein transport; peptide hormone processing; regulation of hormone secretion
 SCG5 ELISA Kit
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