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Neuronal cell adhesion molecule

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Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons (By similarity). Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons . Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

Below are the list of possible Neuronal cell adhesion molecule products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Neuronal cell adhesion molecule

 Neuronal cell adhesion molecule ELISA Kit
 Neuronal cell adhesion molecule Recombinant
 Neuronal cell adhesion molecule Antibody
Also known as Neuronal cell adhesion molecule (Nr-CAM) (Ankyrin-binding cell adhesion molecule NrCAM) (Neuronal surface protein Bravo) (rBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related).
NRCAM: Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier. Belongs to the immunoglobulin superfamily. L1/n
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eurofascin/NgCAM family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Cellular Component: axon; plasma membrane; synapse

Molecular Function: ankyrin binding

Biological Process: action potential propagation; angiogenesis; axon guidance; cell adhesion; cell-cell adhesion; central nervous system development; clustering of voltage-gated sodium channels; heterotypic cell-cell adhesion; protein localization; retinal ganglion cell axon guidance
 Nrcam ELISA Kit
 Nrcam Recombinant
 Nrcam Antibody
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