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Neuronal membrane glycoprotein

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Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Below are the list of possible Neuronal membrane glycoprotein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Neuronal membrane glycoprotein M6-a

 Neuronal membrane glycoprotein M6-a ELISA Kit
 Neuronal membrane glycoprotein M6-a Recombinant
 Neuronal membrane glycoprotein M6-a Antibody
Also known as Neuronal membrane glycoprotein M6-a (M6a).
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src s
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ignaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.

Protein type: Cell surface; Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4q34

Cellular Component: cell soma; filopodium; neuron projection; plasma membrane

Molecular Function: protein binding

Biological Process: neurite morphogenesis; neuron migration; positive regulation of filopodium formation; stem cell differentiation; synaptogenesis
 GPM6A ELISA Kit
 GPM6A Recombinant
 GPM6A Antibody
 M6A ELISA Kit
 M6A Recombinant
 M6A Antibody
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Neuronal membrane glycoprotein M6-b

 Neuronal membrane glycoprotein M6-b ELISA Kit
 Neuronal membrane glycoprotein M6-b Recombinant
 Neuronal membrane glycoprotein M6-b Antibody
Also known as Neuronal membrane glycoprotein M6-b (M6b).
GPM6B: May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. Belongs to t
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he myelin proteolipid protein family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xp22.2

Cellular Component: lipid raft; plasma membrane

Biological Process: negative regulation of serotonin uptake; positive regulation of bone mineralization; regulation of actin cytoskeleton organization and biogenesis; regulation of focal adhesion formation
 GPM6B ELISA Kit
 GPM6B Recombinant
 GPM6B Antibody
 M6B ELISA Kit
 M6B Recombinant
 M6B Antibody
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