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Neuropilin and tolloid-like protein

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Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity).

Below are the list of possible Neuropilin and tolloid-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Neuropilin and tolloid-like protein 1

 Neuropilin and tolloid-like protein 1 ELISA Kit
 Neuropilin and tolloid-like protein 1 Recombinant
 Neuropilin and tolloid-like protein 1 Antibody
Also known as Neuropilin and tolloid-like protein 1 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).
NETO1: a transmembrane protein and component of the N-methyl-D-aspartate receptor (NMDAR) complex. Required to maintain the normal level of NMDAR subunits at synapses. The NMDAR complex is a major excitatory ligand-gated ion channel in the cen
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tral nervous system and a major mediator of synaptic plasticity. Important in the development and/or maintenance of neuronal circuitry. Neto1-deficient mice have a dramatic decrease in the number of NMDA receptors at synapses, impairing learning and synaptic plasticity. Three isoforms of the human protein are produced by alternative splicing. Isoforms 1 and 2 are retina-specific whereas isoform 3 is found in retina as well as at lower levels in adult and fetal brain.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q22.2

Cellular Component: excitatory synapse; postsynaptic density

Biological Process: memory; regulation of long-term neuronal synaptic plasticity; visual learning
 NETO1 ELISA Kit
 NETO1 Recombinant
 NETO1 Antibody
 BTCL1 ELISA Kit
 BTCL1 Recombinant
 BTCL1 Antibody
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Neuropilin and tolloid-like protein 2

 Neuropilin and tolloid-like protein 2 ELISA Kit
 Neuropilin and tolloid-like protein 2 Recombinant
 Neuropilin and tolloid-like protein 2 Antibody
Also known as Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).
NETO2: Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs),
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thus directly influencing synaptic transmission. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q11
 NETO2 ELISA Kit
 NETO2 Recombinant
 NETO2 Antibody
 BTCL2 ELISA Kit
 BTCL2 Recombinant
 BTCL2 Antibody
 UNQ1926/PRO4401 ELISA Kit
 UNQ1926/PRO4401 Recombinant
 UNQ1926/PRO4401 Antibody
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