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Nexilin

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Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.

Below are the list of possible Nexilin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nexilin

 Nexilin ELISA Kit
 Nexilin Recombinant
 Nexilin Antibody
NEXN: Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity. Defects in NEXN are the cause of cardiomyopathy dilated type 1CC (CMD1CC). A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk
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of premature death. Defects in NEXN are the cause of familial hypertrophic cardiomyopathy type 20 (CMH20). CMH20 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Cellular Component: cell-substrate adherens junction; focal adhesion; Z disc

Molecular Function: actin filament binding; structural constituent of muscle

Biological Process: cardiac muscle fiber development; regulation of cell migration; regulation of cytoskeleton organization and biogenesis
 Nexn ELISA Kit
 Nexn Recombinant
 Nexn Antibody
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