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Niemann-Pick C1-like protein

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Plays a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption (By similarity). Lack of activity leads to multiple lipid transport defects. The protein may have a function in the transport of multiple lipids and their homeostasis. Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation (By similarity).

Below are the list of possible Niemann-Pick C1-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Niemann-Pick C1-like protein 1

 Niemann-Pick C1-like protein 1 ELISA Kit
 Niemann-Pick C1-like protein 1 Recombinant
 Niemann-Pick C1-like protein 1 Antibody
mouse homolog plays a role in intestinal cholesterol absorption [RGD, Feb 2006]
 Npc1l1 ELISA Kit
 Npc1l1 Recombinant
 Npc1l1 Antibody
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