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NKG2-D type II integral membrane protein

Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins.

Below are the list of possible NKG2-D type II integral membrane protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

NKG2-D type II integral membrane protein

 NKG2-D type II integral membrane protein ELISA Kit
 NKG2-D type II integral membrane protein Recombinant
 NKG2-D type II integral membrane protein Antibody
Also known as NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NK lectin-like receptor) (NKLLR) (NKG2-D-activating NK receptor) (NKR-P2) (CD antigen CD314).
functions as a natural cytotoxicity receptor to stimulate perforin-mediated elimination of ligand-expressing tumor cells [RGD, Feb 2006]
 Klrk1 ELISA Kit
 Klrk1 Recombinant
 Klrk1 Antibody
 Nkg2d ELISA Kit
 Nkg2d Recombinant
 Nkg2d Antibody
 Nkrp2 ELISA Kit
 Nkrp2 Recombinant
 Nkrp2 Antibody
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