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NLR family CARD domain-containing protein

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Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.

Below are the list of possible NLR family CARD domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NLR family CARD domain-containing protein 4

 NLR family CARD domain-containing protein 4 ELISA Kit
 NLR family CARD domain-containing protein 4 Recombinant
 NLR family CARD domain-containing protein 4 Antibody
Also known as NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (Clan protein) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf).
NLRC4: Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Orth
>>>
olog: 2p22.3

Cellular Component: cytosol; nucleus; spindle microtubule

Molecular Function: ATP binding; cysteine protease inhibitor activity; identical protein binding; magnesium ion binding; protein binding; protein homodimerization activity; ubiquitin-protein ligase activity

Biological Process: activation of innate immune response; activation of NF-kappaB transcription factor; caspase activation; defense response to bacterium; detection of bacterium; inflammatory response; innate immune response; interleukin-1 beta secretion; positive regulation of apoptosis; protein homooligomerization; regulation of apoptosis; regulation of signal transduction

Disease: Autoinflammation With Infantile Enterocolitis; Familial Cold Autoinflammatory Syndrome 4
 NLRC4 ELISA Kit
 NLRC4 Recombinant
 NLRC4 Antibody
 CARD12 ELISA Kit
 CARD12 Recombinant
 CARD12 Antibody
 CLAN ELISA Kit
 CLAN Recombinant
 CLAN Antibody
 CLAN1 ELISA Kit
 CLAN1 Recombinant
 CLAN1 Antibody
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