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NLR family pyrin domain-containing protein

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May function as a negative regulator of NF-kappa-B by preventing RELA/p65 phosphorylation at 'Ser-536', thereby inhibiting its transcriptional activity. Through NF-kappa-B regulation may control cytokine release upon Toll-like receptors activation and therefore play a role in modulation of innate immunity. May also play a role in cell cycle progression and apoptotic process.

Below are the list of possible NLR family pyrin domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

NLR family pyrin domain-containing protein 2B

 NLR family pyrin domain-containing protein 2B ELISA Kit
 NLR family pyrin domain-containing protein 2B Recombinant
 NLR family pyrin domain-containing protein 2B Antibody
Also known as NLR family pyrin domain-containing protein 2B (Pyrin domain-containing protein 2-like protein POP4) (Pyrin-only protein 4).
NLRP2B: May function as a negative regulator of NF-kappa-B by preventing RELA/p65 phosphorylation at 'Ser-536', thereby inhibiting its transcriptional activity. Through NF-kappa-B regulation may control cytokine release upon Toll-like receptors activation and therefore play a role in modulation of innate immunity. May also play a role in cell cycle progression and apoptotic process. {ECO:0000269|PubMed:24871464}. Up-regulated by inflammatory stimulus (LPS
>>>
). {ECO:0000269|PubMed:24871464}

Cellular Component: cytoplasm; nucleus

Biological Process: inhibition of NF-kappaB transcription factor; negative regulation of cell cycle; negative regulation of interleukin-1 beta secretion; negative regulation of peptidyl-serine phosphorylation; negative regulation of toll-like receptor signaling pathway; positive regulation of apoptosis
 NLRP2B ELISA Kit
 NLRP2B Recombinant
 NLRP2B Antibody
 CLRX.1 ELISA Kit
 CLRX.1 Recombinant
 CLRX.1 Antibody
 NLRP2P ELISA Kit
 NLRP2P Recombinant
 NLRP2P Antibody
 NOD24 ELISA Kit
 NOD24 Recombinant
 NOD24 Antibody
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