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Nocturnin

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Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly(A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase-independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity).

Below are the list of possible Nocturnin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nocturnin

 Nocturnin ELISA Kit
 Nocturnin Recombinant
 Nocturnin Antibody
Also known as Nocturnin (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC).
mouse homolog may be involved in circadian rhythm [RGD, Feb 2006]
 Noct ELISA Kit
 Noct Recombinant
 Noct Antibody
 Ccr4 ELISA Kit
 Ccr4 Recombinant
 Ccr4 Antibody
 Ccrn4l ELISA Kit
 Ccrn4l Recombinant
 Ccrn4l Antibody
 Noc ELISA Kit
 Noc Recombinant
 Noc Antibody
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