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Non-homologous end-joining factor

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DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary .

Below are the list of possible Non-homologous end-joining factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Non-homologous end-joining factor 1

 Non-homologous end-joining factor 1 ELISA Kit
 Non-homologous end-joining factor 1 Recombinant
 Non-homologous end-joining factor 1 Antibody
Also known as Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).
NHEJ1: DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow
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XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. Interacts with XRCC4 and the XRCC4-LIG4 complex. Binds DNA in a length-dependent manner. Ubiquitously expressed. Belongs to the XLF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage

Cellular Component: DNA ligase IV complex; nucleus

Molecular Function: DNA end binding

Biological Process: B cell differentiation; double-strand break repair via nonhomologous end joining; response to ionizing radiation; T cell differentiation
 Nhej1 ELISA Kit
 Nhej1 Recombinant
 Nhej1 Antibody
 Xlf ELISA Kit
 Xlf Recombinant
 Xlf Antibody
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