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Non-receptor tyrosine-protein kinase

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Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Below are the list of possible Non-receptor tyrosine-protein kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Non-receptor tyrosine-protein kinase TNK1

 Non-receptor tyrosine-protein kinase TNK1 ELISA Kit
 Non-receptor tyrosine-protein kinase TNK1 Recombinant
 Non-receptor tyrosine-protein kinase TNK1 Antibody
Also known as Non-receptor tyrosine-protein kinase TNK1 (CD38 negative kinase 1).
TNK1: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could s
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pecifically be involved in phospholipid signal transduction. Interacts with the SH3 domain of PLCG1 via its Pro-rich domain. Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain. Belongs to the protein kinase superfamily. Tyr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ack family; EC 2.7.10.2; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; extrinsic to internal side of plasma membrane; membrane

Molecular Function: ATP binding; protein binding; protein-tyrosine kinase activity; receptor binding; signal transducer activity

Biological Process: cell differentiation; innate immune response; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway
 TNK1 ELISA Kit
 TNK1 Recombinant
 TNK1 Antibody
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Non-receptor tyrosine-protein kinase TYK2

 Non-receptor tyrosine-protein kinase TYK2 ELISA Kit
 Non-receptor tyrosine-protein kinase TYK2 Recombinant
 Non-receptor tyrosine-protein kinase TYK2 Antibody
Tyk2: a non-receptor tyrosine-protein kinase of the JakA family. Activated in signaling from the IL-2, gp130 and IFN families of receptors. Phosphorylates the interferon-alpha/beta receptor alpha chain.

Protein type: EC 2.7.10.2; JakA family; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group

Chromosomal Location of Human Ortholog: 19p13.2

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Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; nucleus

Molecular Function: growth hormone receptor binding; protein binding; protein-tyrosine kinase activity

Biological Process: cell differentiation; cell migration; innate immune response; protein amino acid phosphorylation; regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway

Disease: Immunodeficiency 35
 TYK2 ELISA Kit
 TYK2 Recombinant
 TYK2 Antibody
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