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Nuclear inhibitor of protein phosphatase

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Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.; Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing.

Below are the list of possible Nuclear inhibitor of protein phosphatase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nuclear inhibitor of protein phosphatase 1

 Nuclear inhibitor of protein phosphatase 1 ELISA Kit
 Nuclear inhibitor of protein phosphatase 1 Recombinant
 Nuclear inhibitor of protein phosphatase 1 Antibody
Also known as Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).
NIPP-1: Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.-; Inhibitor; Motility/polarity/chemotaxis; Protein
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phosphatase, regulatory subunit; Ribonuclease

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: nuclear speck; nucleoplasm; nucleus

Molecular Function: mRNA binding; protein binding; ribonuclease E activity; RNA binding; type 1 serine/threonine specific protein phosphatase inhibitor activity

Biological Process: negative regulation of protein amino acid dephosphorylation; RNA catabolic process
 PPP1R8 ELISA Kit
 PPP1R8 Recombinant
 PPP1R8 Antibody
 ARD1 ELISA Kit
 ARD1 Recombinant
 ARD1 Antibody
 NIPP1 ELISA Kit
 NIPP1 Recombinant
 NIPP1 Antibody
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