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Nuclear mitotic apparatus protein

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Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume .

Below are the list of possible Nuclear mitotic apparatus protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nuclear mitotic apparatus protein 1

 Nuclear mitotic apparatus protein 1 ELISA Kit
 Nuclear mitotic apparatus protein 1 Recombinant
 Nuclear mitotic apparatus protein 1 Antibody
Also known as Nuclear mitotic apparatus protein 1 (NuMA protein) (Nuclear matrix protein-22) (NMP-22) (SP-H antigen).
NuMA-1: a coiled-coil nuclear protein that is required to establish and maintain mammalian spindle poles. Dissociates from condensing chromosomes during early prophase, before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident. Two human splice-variant isoforms have been described.

Protein
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type: Cell cycle regulation; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cell cortex; centrosome; cytoplasm; cytosol; nucleoplasm; nucleus; spindle; spindle microtubule; spindle pole

Molecular Function: protein binding; structural molecule activity

Biological Process: nuclear organization and biogenesis

Disease: Acute Promyelocytic Leukemia
 NUMA1 ELISA Kit
 NUMA1 Recombinant
 NUMA1 Antibody
 NMP22 ELISA Kit
 NMP22 Recombinant
 NMP22 Antibody
 NUMA ELISA Kit
 NUMA Recombinant
 NUMA Antibody
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