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Nuclear pore glycoprotein

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Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.

Below are the list of possible Nuclear pore glycoprotein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nuclear pore glycoprotein p62

 Nuclear pore glycoprotein p62 ELISA Kit
 Nuclear pore glycoprotein p62 Recombinant
 Nuclear pore glycoprotein p62 Antibody
Also known as Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62).
NUP62: Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex. Defects in NUP62 are the cause of i
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nfantile striatonigral degeneration (SNDI); also known as infantile bilateral striatal necrosis (IBSN) or familial striatal degeneration. SNDI is a neurological disorder characterized by symmetrical degeneration of the caudate nucleus, putamen and occasionally the globus pallidus, with little involvement of the rest of the brain. The clinical features include developmental regression, choreoathetosis, dystonia, spasticity, dysphagia, failure to thrive, nystagmus, optic atrophy and mental retardation. Belongs to the nucleoporin NSP1/NUP62 family.

Protein type: Adaptor/scaffold; Nucleoporin

Cellular Component: annulate lamellae; intracellular membrane-bound organelle; nuclear envelope; nuclear membrane; nuclear pore; protein complex; ribonucleoprotein complex

Molecular Function: Hsp70 protein binding; Hsp90 protein binding; kinesin binding; nucleocytoplasmic transporter activity; phospholipid binding; protein binding; PTB domain binding; receptor signaling complex scaffold activity; SH2 domain binding; structural constituent of nuclear pore; thyroid hormone receptor binding; ubiquitin binding

Biological Process: cell aging; cell death; cell surface receptor linked signal transduction; mitosis; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of MAP kinase activity; negative regulation of programmed cell death; negative regulation of Ras protein signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; protein import into nucleus; regulation of protein import into nucleus; RNA export from nucleus; spermatogenesis; transcription, DNA-dependent
 Nup62 ELISA Kit
 Nup62 Recombinant
 Nup62 Antibody
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