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Nucleolysin

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Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis (By similarity).

Below are the list of possible Nucleolysin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Nucleolysin TIA-1

 Nucleolysin TIA-1 ELISA Kit
 Nucleolysin TIA-1 Recombinant
 Nucleolysin TIA-1 Antibody
Also known as Nucleolysin TIA-1 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1).
TIA1: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. 2 isoform
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s of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Translation

Cellular Component: cytoplasm; nucleoplasm; nucleus; ribonucleoprotein complex; stress granule

Molecular Function: AU-rich element binding

Biological Process: negative regulation of cytokine biosynthetic process; negative regulation of translation; regulation of nuclear mRNA splicing, via spliceosome
 Tia1 ELISA Kit
 Tia1 Recombinant
 Tia1 Antibody
 Tia ELISA Kit
 Tia Recombinant
 Tia Antibody
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Nucleolysin TIA-1 isoform p40

 Nucleolysin TIA-1 isoform p40 ELISA Kit
 Nucleolysin TIA-1 isoform p40 Recombinant
 Nucleolysin TIA-1 isoform p40 Antibody
Also known as Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1).
TIA1: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved
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in apoptosis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 2p13

Cellular Component: cytoplasm; nucleoplasm; stress granule

Molecular Function: poly(A) binding; protein binding

Biological Process: fibroblast growth factor receptor signaling pathway; regulation of nuclear mRNA splicing, via spliceosome

Disease: Welander Distal Myopathy
 TIA1 ELISA Kit
 TIA1 Recombinant
 TIA1 Antibody
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Nucleolysin TIAR

 Nucleolysin TIAR ELISA Kit
 Nucleolysin TIAR Recombinant
 Nucleolysin TIAR Antibody
Also known as Nucleolysin TIAR (TIA-1-related protein).
TIAL1: a member of a family of RNA-binding proteins that possesses nucleolytic activity. A cytotoxic T cell granule-associated protein that has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. Members of this protein family may be involved in the induction of apoptosis. Two splice
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variant isoforms have been described.

Protein type: Apoptosis; RNA-binding

Cellular Component: cytoplasm; nucleus; ribonucleoprotein complex; stress granule

Molecular Function: AU-rich element binding

Biological Process: germ cell development; positive regulation of cell proliferation; stem cell division
 Tial1 ELISA Kit
 Tial1 Recombinant
 Tial1 Antibody
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