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Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). AMO1 is specifically important for nuclear protein and mRNA export.
Below are the list of possible Nucleoporin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications. |
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Nucleoporin NSP1 ELISA Kit Nucleoporin NSP1 Recombinant Nucleoporin NSP1 Antibody | Also known as Nucleoporin NSP1 (Nuclear pore protein NSP1) (Nucleoskeletal-like protein). Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assur >>> ed by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NSP1 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, pre-ribosome, signal recognition particle (SRP), and protein transport. |
NSP1 ELISA Kit NSP1 Recombinant NSP1 Antibody | CTHT_0054390 ELISA Kit CTHT_0054390 Recombinant CTHT_0054390 Antibody |
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Nucleoporin NUP1 ELISA Kit Nucleoporin NUP1 Recombinant Nucleoporin NUP1 Antibody | Also known as Nucleoporin NUP1 (Nuclear pore protein NUP1). Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in >>> the nucleus, with GDP in the cytoplasm). As one of the FG repeat nucleoporins NUP1 is involved in interactions with and guidance of nuclear transport receptors such as SRP1-KAP95 (importin alpha and beta) through the NPC. Like the closely related NUP2 it also plays an important role in disassembling and recycling SRP1-KAP95 to the cytoplasm after nuclear import. Upon entry of the heterotrimeric SRP1-KAP95-cargo complex in the nucleus, NUP1 binds through its C-terminus to KAP95, thus accelerating the release of KAP95 and, indirectly, of the nuclear localization signal (NLS)-containing cargo from the SRP1-KAP95-cargo complex. |
NUP1 ELISA Kit NUP1 Recombinant NUP1 Antibody | YOR098C ELISA Kit YOR098C Recombinant YOR098C Antibody |
YOR3182C ELISA Kit YOR3182C Recombinant YOR3182C Antibody |
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Nucleoporin NUP145 ELISA Kit Nucleoporin NUP145 Recombinant Nucleoporin NUP145 Antibody | Also known as Nucleoporin NUP145 (Nuclear pore protein NUP145). Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) >>> repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. NUP145 is autocatalytically cleaved in vivo in 2 polypeptides which assume different functions in the NPC. NUP145N as one of the FG repeat nucleoporins participates in karyopherin interactions and contains part of the autocatalytic cleavage activity. NUP145C as part of the NUP84 complex is involved in nuclear poly(A)+ RNA and tRNA export. |
NUP145 ELISA Kit NUP145 Recombinant NUP145 Antibody | CTHT_0042590 ELISA Kit CTHT_0042590 Recombinant CTHT_0042590 Antibody |
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Nucleoporin NUP2 ELISA Kit Nucleoporin NUP2 Recombinant Nucleoporin NUP2 Antibody | Also known as Nucleoporin NUP2 (Nuclear pore protein NUP2) (p95). Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with >>> GTP in the nucleus, with GDP in the cytoplasm). As one of the FG repeat nucleoporins NUP2 is involved in interactions with and guidance of nuclear transport receptors such as SRP1-KAP95 (importin alpha and beta) through the NPC. Like the closely related NUP1 it also plays an important role in disassembling and recycling SRP1-KAP95 to the cytoplasm after nuclear import. Upon entry of the heterotrimeric SRP1-KAP95-cargo complex in the nucleus, NUP2 binds through its N-terminus to the SRP1 nuclear localization signal (NLS) binding site, thus accelerating the release of the NLS-cargo. SRP1 in turn is released from NUP2 by binding of the GSP1-GTP associated export factor CSE1. NUP2 may also have a chromatin boundary/insulator activity through indirect interaction with genomic DNA via CSE1 and blocking of heterochromatin spreading. |
NUP2 ELISA Kit NUP2 Recombinant NUP2 Antibody | YLR335W ELISA Kit YLR335W Recombinant YLR335W Antibody |
L8300.9 ELISA Kit L8300.9 Recombinant L8300.9 Antibody |
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Nucleoporin NUP53 ELISA Kit Nucleoporin NUP53 Recombinant Nucleoporin NUP53 Antibody | Also known as Nucleoporin NUP53 (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44) (Nuclear pore complex protein Nup53) (Nucleoporin Nup35). NUP35: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC. Belongs to the Nup53 family.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 2q32.1< >>> br> Cellular Component: intermediate filament cytoskeleton; intracellular membrane-bound organelle; nuclear envelope; nuclear membrane; nucleoplasm; plasma membrane
Molecular Function: nucleocytoplasmic transporter activity; phospholipid binding; protein binding; single-stranded DNA binding
Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; NLS-bearing substrate import into nucleus; nuclear pore organization and biogenesis; protein sumoylation; regulation of transcription, DNA-dependent; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
NUP35 ELISA Kit NUP35 Recombinant NUP35 Antibody | MP44 ELISA Kit MP44 Recombinant MP44 Antibody |
NUP53 ELISA Kit NUP53 Recombinant NUP53 Antibody |
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Nucleoporin p54 ELISA Kit Nucleoporin p54 Recombinant Nucleoporin p54 Antibody | Also known as Nucleoporin p54 (54 kDa nucleoporin). NUP54: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP54 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: nuclear envelope >>>r> Molecular Function: nucleocytoplasmic transporter activity; protein binding; structural constituent of nuclear pore
Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; NLS-bearing substrate import into nucleus; nuclear pore organization and biogenesis; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
NUP54 ELISA Kit NUP54 Recombinant NUP54 Antibody |
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Nucleoporin p58/p45 ELISA Kit Nucleoporin p58/p45 Recombinant Nucleoporin p58/p45 Antibody | Also known as Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1). NUPL1: a nuclear pore protein. Component of the p62 complex which includes NUP62, NUP54, and NUPL1. Interacts with NUTF2, and with KPNA2 and KPNB1 proteins when they are together, but not with KPNA2 alone. Located in the central region of the nuclear pore complex, biased towards thecytoplasmic side. Contains FG >>> repeats. Three isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear import; Nucleoporin
Cellular Component: nuclear envelope; nuclear pore; protein complex
Molecular Function: nuclear localization sequence binding; nucleocytoplasmic transporter activity
Biological Process: nucleocytoplasmic transport; protein heterooligomerization; protein heterotetramerization; protein homooligomerization; protein import into nucleus; regulation of protein import into nucleus |
Nup58 ELISA Kit Nup58 Recombinant Nup58 Antibody | Nupl1 ELISA Kit Nupl1 Recombinant Nupl1 Antibody |
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